Information-rich localization microscopy through machine learning
Single-molecule methods often rely on point spread functions that are tailored to interpret specific information. Here the authors use a neural network to extract complex PSF information from experimental images, and demonstrate this by classifying color and axial positions of emitters.
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Nature Portfolio
2019
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oai:doaj.org-article:d16a8683e3b8455ab94be76774f148ad2021-12-02T16:58:01ZInformation-rich localization microscopy through machine learning10.1038/s41467-019-10036-z2041-1723https://doaj.org/article/d16a8683e3b8455ab94be76774f148ad2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10036-zhttps://doaj.org/toc/2041-1723Single-molecule methods often rely on point spread functions that are tailored to interpret specific information. Here the authors use a neural network to extract complex PSF information from experimental images, and demonstrate this by classifying color and axial positions of emitters.Taehwan KimSeonah MoonKe XuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019) |
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Science Q Taehwan Kim Seonah Moon Ke Xu Information-rich localization microscopy through machine learning |
description |
Single-molecule methods often rely on point spread functions that are tailored to interpret specific information. Here the authors use a neural network to extract complex PSF information from experimental images, and demonstrate this by classifying color and axial positions of emitters. |
format |
article |
author |
Taehwan Kim Seonah Moon Ke Xu |
author_facet |
Taehwan Kim Seonah Moon Ke Xu |
author_sort |
Taehwan Kim |
title |
Information-rich localization microscopy through machine learning |
title_short |
Information-rich localization microscopy through machine learning |
title_full |
Information-rich localization microscopy through machine learning |
title_fullStr |
Information-rich localization microscopy through machine learning |
title_full_unstemmed |
Information-rich localization microscopy through machine learning |
title_sort |
information-rich localization microscopy through machine learning |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/d16a8683e3b8455ab94be76774f148ad |
work_keys_str_mv |
AT taehwankim informationrichlocalizationmicroscopythroughmachinelearning AT seonahmoon informationrichlocalizationmicroscopythroughmachinelearning AT kexu informationrichlocalizationmicroscopythroughmachinelearning |
_version_ |
1718382416593158144 |