Optically-controlled bacterial metabolite for cancer therapy
Targeting tumors with bacteria as vehicles for metabolite therapy suffers from low efficiency and robustness. Here, the authors combine carbon nitride with nitric oxide generation enzyme-positive E. coli for photo-controlled metabolite therapy (PMT) and observe increased effects both in vitro and in...
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Nature Portfolio
2018
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oai:doaj.org-article:d16bc80f86904250a7bda65fe72492612021-12-02T17:31:57ZOptically-controlled bacterial metabolite for cancer therapy10.1038/s41467-018-03233-92041-1723https://doaj.org/article/d16bc80f86904250a7bda65fe72492612018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03233-9https://doaj.org/toc/2041-1723Targeting tumors with bacteria as vehicles for metabolite therapy suffers from low efficiency and robustness. Here, the authors combine carbon nitride with nitric oxide generation enzyme-positive E. coli for photo-controlled metabolite therapy (PMT) and observe increased effects both in vitro and in tumor-bearing mice.Di-Wei ZhengYing ChenZi-Hao LiLu XuChu-Xin LiBin LiJin-Xuan FanSi-Xue ChengXian-Zheng ZhangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Di-Wei Zheng Ying Chen Zi-Hao Li Lu Xu Chu-Xin Li Bin Li Jin-Xuan Fan Si-Xue Cheng Xian-Zheng Zhang Optically-controlled bacterial metabolite for cancer therapy |
description |
Targeting tumors with bacteria as vehicles for metabolite therapy suffers from low efficiency and robustness. Here, the authors combine carbon nitride with nitric oxide generation enzyme-positive E. coli for photo-controlled metabolite therapy (PMT) and observe increased effects both in vitro and in tumor-bearing mice. |
format |
article |
author |
Di-Wei Zheng Ying Chen Zi-Hao Li Lu Xu Chu-Xin Li Bin Li Jin-Xuan Fan Si-Xue Cheng Xian-Zheng Zhang |
author_facet |
Di-Wei Zheng Ying Chen Zi-Hao Li Lu Xu Chu-Xin Li Bin Li Jin-Xuan Fan Si-Xue Cheng Xian-Zheng Zhang |
author_sort |
Di-Wei Zheng |
title |
Optically-controlled bacterial metabolite for cancer therapy |
title_short |
Optically-controlled bacterial metabolite for cancer therapy |
title_full |
Optically-controlled bacterial metabolite for cancer therapy |
title_fullStr |
Optically-controlled bacterial metabolite for cancer therapy |
title_full_unstemmed |
Optically-controlled bacterial metabolite for cancer therapy |
title_sort |
optically-controlled bacterial metabolite for cancer therapy |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/d16bc80f86904250a7bda65fe7249261 |
work_keys_str_mv |
AT diweizheng opticallycontrolledbacterialmetaboliteforcancertherapy AT yingchen opticallycontrolledbacterialmetaboliteforcancertherapy AT zihaoli opticallycontrolledbacterialmetaboliteforcancertherapy AT luxu opticallycontrolledbacterialmetaboliteforcancertherapy AT chuxinli opticallycontrolledbacterialmetaboliteforcancertherapy AT binli opticallycontrolledbacterialmetaboliteforcancertherapy AT jinxuanfan opticallycontrolledbacterialmetaboliteforcancertherapy AT sixuecheng opticallycontrolledbacterialmetaboliteforcancertherapy AT xianzhengzhang opticallycontrolledbacterialmetaboliteforcancertherapy |
_version_ |
1718380458931126272 |