Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling

Actin-based structures in cells and tissues are built and maintained through a poorly understood balance between assembly and disassembly. Here, our findings provide insights into how factors known to promote these opposing effects dynamically integrate to shape cells and tissue systems.

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Autores principales:	Elena E. Grintsevich, Giasuddin Ahmed, Anush A. Ginosyan, Heng Wu, Shannon K. Rich, Emil Reisler, Jonathan R. Terman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d16f206bcaf8453d98be0d77c264773a
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spelling	oai:doaj.org-article:d16f206bcaf8453d98be0d77c264773a2021-12-02T17:27:04ZProfilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling10.1038/s41467-021-25781-32041-1723https://doaj.org/article/d16f206bcaf8453d98be0d77c264773a2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25781-3https://doaj.org/toc/2041-1723Actin-based structures in cells and tissues are built and maintained through a poorly understood balance between assembly and disassembly. Here, our findings provide insights into how factors known to promote these opposing effects dynamically integrate to shape cells and tissue systems.Elena E. GrintsevichGiasuddin AhmedAnush A. GinosyanHeng WuShannon K. RichEmil ReislerJonathan R. TermanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elena E. Grintsevich Giasuddin Ahmed Anush A. Ginosyan Heng Wu Shannon K. Rich Emil Reisler Jonathan R. Terman Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
description	Actin-based structures in cells and tissues are built and maintained through a poorly understood balance between assembly and disassembly. Here, our findings provide insights into how factors known to promote these opposing effects dynamically integrate to shape cells and tissue systems.
format	article
author	Elena E. Grintsevich Giasuddin Ahmed Anush A. Ginosyan Heng Wu Shannon K. Rich Emil Reisler Jonathan R. Terman
author_facet	Elena E. Grintsevich Giasuddin Ahmed Anush A. Ginosyan Heng Wu Shannon K. Rich Emil Reisler Jonathan R. Terman
author_sort	Elena E. Grintsevich
title	Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
title_short	Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
title_full	Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
title_fullStr	Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
title_full_unstemmed	Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
title_sort	profilin and mical combine to impair f-actin assembly and promote disassembly and remodeling
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d16f206bcaf8453d98be0d77c264773a
work_keys_str_mv	AT elenaegrintsevich profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling AT giasuddinahmed profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling AT anushaginosyan profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling AT hengwu profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling AT shannonkrich profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling AT emilreisler profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling AT jonathanrterman profilinandmicalcombinetoimpairfactinassemblyandpromotedisassemblyandremodeling
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Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling

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