STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and provide a mechanism for its requirement in antige...

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Autores principales:	Paula Nunes-Hasler, Sophia Maschalidi, Carla Lippens, Cyril Castelbou, Samuel Bouvet, Daniele Guido, Flavien Bermont, Esen Y. Bassoy, Nicolas Page, Doron Merkler, Stéphanie Hugues, Denis Martinvalet, Bénédicte Manoury, Nicolas Demaurex
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d16f804a8f3d4c7abd46394836e7b3e1
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spelling	oai:doaj.org-article:d16f804a8f3d4c7abd46394836e7b3e12021-12-02T15:38:51ZSTIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells10.1038/s41467-017-01600-62041-1723https://doaj.org/article/d16f804a8f3d4c7abd46394836e7b3e12017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01600-6https://doaj.org/toc/2041-1723STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and provide a mechanism for its requirement in antigen cross-presentation.Paula Nunes-HaslerSophia MaschalidiCarla LippensCyril CastelbouSamuel BouvetDaniele GuidoFlavien BermontEsen Y. BassoyNicolas PageDoron MerklerStéphanie HuguesDenis MartinvaletBénédicte ManouryNicolas DemaurexNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paula Nunes-Hasler Sophia Maschalidi Carla Lippens Cyril Castelbou Samuel Bouvet Daniele Guido Flavien Bermont Esen Y. Bassoy Nicolas Page Doron Merkler Stéphanie Hugues Denis Martinvalet Bénédicte Manoury Nicolas Demaurex STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
description	STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and provide a mechanism for its requirement in antigen cross-presentation.
format	article
author	Paula Nunes-Hasler Sophia Maschalidi Carla Lippens Cyril Castelbou Samuel Bouvet Daniele Guido Flavien Bermont Esen Y. Bassoy Nicolas Page Doron Merkler Stéphanie Hugues Denis Martinvalet Bénédicte Manoury Nicolas Demaurex
author_facet	Paula Nunes-Hasler Sophia Maschalidi Carla Lippens Cyril Castelbou Samuel Bouvet Daniele Guido Flavien Bermont Esen Y. Bassoy Nicolas Page Doron Merkler Stéphanie Hugues Denis Martinvalet Bénédicte Manoury Nicolas Demaurex
author_sort	Paula Nunes-Hasler
title	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
title_short	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
title_full	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
title_fullStr	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
title_full_unstemmed	STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
title_sort	stim1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d16f804a8f3d4c7abd46394836e7b3e1
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STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

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