Compartment‐specific 13C metabolic flux analysis reveals boosted NADPH availability coinciding with increased cell‐specific productivity for IgG1 producing CHO cells after MTA treatment
Abstract Increasing cell‐specific productivities (CSPs) for the production of heterologous proteins in Chinese hamster ovary (CHO) cells is an omnipresent need in the biopharmaceutical industry. The novel additive 5′‐deoxy‐5′‐(methylthio)adenosine (MTA), a chemical degradation product of S‐(5′‐adeno...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Wiley-VCH
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/d171d3039cfe4829ada3ee91d61b3840 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|