Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy

Background: The role of flexible bronchoscopy in diagnosis of peripheral pulmonary neoplasia remains controversial. Aim of the work: To assess the diagnostic yield of non-guided flexible bronchoscopy biopsy techniques in diagnosis of peripherally located bronchogenic carcinoma. Patients and Method...

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Autor principal:	Sawsan Elsawy
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	non-guided flexible bronchoscopy peripheral bronchogenic carcinoma diagnostic yield Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d173efe609b04952afd1b409ebb305ad
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spelling	oai:doaj.org-article:d173efe609b04952afd1b409ebb305ad2021-12-02T10:38:27ZDiagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy2636-41742682-378010.21608/ijma.2020.28841.1120https://doaj.org/article/d173efe609b04952afd1b409ebb305ad2020-07-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_94569_5242c14323a70d646bdd89a6c615fb42.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: The role of flexible bronchoscopy in diagnosis of peripheral pulmonary neoplasia remains controversial. Aim of the work: To assess the diagnostic yield of non-guided flexible bronchoscopy biopsy techniques in diagnosis of peripherally located bronchogenic carcinoma. Patients and Methods:This cross-sectional study was conducted on 49 out of 85 patients with confirmed bronchogenic carcinoma; they were subjected to flexible bronchoscopy forceps biopsy [FB], bronchoalveolar lavage [BAL], transbronchial needle aspiration [TBNA], and bronchial brushing [BB]. Results: Diagnostic yield of bronchoscopy was positive in 40.8%. The procedures were; BAL in 26.5% of patients with positive yield in 15.0%, FB in 18.4% of patients with positive yield in 70.0%, TBNA in 26.5% of patients with no positive yield [0.0%] and BB in 18.4% of patients with positive yield in 15.0%. More than ≥6 Biopsy were taken in 79.6% and < 6 biopsies was taken in 20.4%. Lesions in the lower lobes had a high diagnostic yield [60.0%] [P0.007]. Lesions > 3cm had a diagnostic yield of 70% compared to 30 % in lesions ≤ 3 cm [P 0.001]. Cases with CT-Bronchus sign had a higher diagnostic yield [85.0%] [p 0.003]. Also, ≥ 6 Biopsy had higher diagnostic yield than those with lesions ˂ 3cm [100.0% and 34.5% respectively] [P 0.003]. The presence of bronchial lesions and its lobar locations had higher diagnostic yield. Conclusion: The diagnostic yield of bronchoscopy in peripherally locating bronchogenic carcinoma depends on a several factors, including lower lobe location, lesion size≥ 3cm, presence of CT bronchus sign, presence of bronchial lesion, and ≥ 6 biopsies.Sawsan ElsawyAl-Azhar University, Faculty of Medicine (Damietta)articlenon-guidedflexible bronchoscopyperipheralbronchogenic carcinomadiagnostic yieldMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 3, Pp 631-638 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	non-guided flexible bronchoscopy peripheral bronchogenic carcinoma diagnostic yield Medicine (General) R5-920
spellingShingle	non-guided flexible bronchoscopy peripheral bronchogenic carcinoma diagnostic yield Medicine (General) R5-920 Sawsan Elsawy Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy
description	Background: The role of flexible bronchoscopy in diagnosis of peripheral pulmonary neoplasia remains controversial. Aim of the work: To assess the diagnostic yield of non-guided flexible bronchoscopy biopsy techniques in diagnosis of peripherally located bronchogenic carcinoma. Patients and Methods:This cross-sectional study was conducted on 49 out of 85 patients with confirmed bronchogenic carcinoma; they were subjected to flexible bronchoscopy forceps biopsy [FB], bronchoalveolar lavage [BAL], transbronchial needle aspiration [TBNA], and bronchial brushing [BB]. Results: Diagnostic yield of bronchoscopy was positive in 40.8%. The procedures were; BAL in 26.5% of patients with positive yield in 15.0%, FB in 18.4% of patients with positive yield in 70.0%, TBNA in 26.5% of patients with no positive yield [0.0%] and BB in 18.4% of patients with positive yield in 15.0%. More than ≥6 Biopsy were taken in 79.6% and < 6 biopsies was taken in 20.4%. Lesions in the lower lobes had a high diagnostic yield [60.0%] [P0.007]. Lesions > 3cm had a diagnostic yield of 70% compared to 30 % in lesions ≤ 3 cm [P 0.001]. Cases with CT-Bronchus sign had a higher diagnostic yield [85.0%] [p 0.003]. Also, ≥ 6 Biopsy had higher diagnostic yield than those with lesions ˂ 3cm [100.0% and 34.5% respectively] [P 0.003]. The presence of bronchial lesions and its lobar locations had higher diagnostic yield. Conclusion: The diagnostic yield of bronchoscopy in peripherally locating bronchogenic carcinoma depends on a several factors, including lower lobe location, lesion size≥ 3cm, presence of CT bronchus sign, presence of bronchial lesion, and ≥ 6 biopsies.
format	article
author	Sawsan Elsawy
author_facet	Sawsan Elsawy
author_sort	Sawsan Elsawy
title	Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy
title_short	Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy
title_full	Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy
title_fullStr	Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy
title_full_unstemmed	Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy
title_sort	diagnosis of peripherally located bronchogenic carcinoma: utility of non-guided flexible bronchoscopy
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/d173efe609b04952afd1b409ebb305ad
work_keys_str_mv	AT sawsanelsawy diagnosisofperipherallylocatedbronchogeniccarcinomautilityofnonguidedflexiblebronchoscopy
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Diagnosis of Peripherally Located Bronchogenic Carcinoma: Utility of Non-Guided Flexible Bronchoscopy

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