3D particle averaging and detection of macromolecular symmetry in localization microscopy

Adaptation of current algorithms to 3D SMLM data is currently problematic. Here the authors report a method that increases the signal-to-noise ratio and resolution of 3D single particle analysis in localization microscopy and enables determination of the symmetry groups of macromolecular complexes.

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Autores principales:	Hamidreza Heydarian, Maarten Joosten, Adrian Przybylski, Florian Schueder, Ralf Jungmann, Ben van Werkhoven, Jan Keller-Findeisen, Jonas Ries, Sjoerd Stallinga, Mark Bates, Bernd Rieger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d17ad19811dd4f2a9819d5862675ea69
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spelling	oai:doaj.org-article:d17ad19811dd4f2a9819d5862675ea692021-12-02T15:55:07Z3D particle averaging and detection of macromolecular symmetry in localization microscopy10.1038/s41467-021-22006-52041-1723https://doaj.org/article/d17ad19811dd4f2a9819d5862675ea692021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22006-5https://doaj.org/toc/2041-1723Adaptation of current algorithms to 3D SMLM data is currently problematic. Here the authors report a method that increases the signal-to-noise ratio and resolution of 3D single particle analysis in localization microscopy and enables determination of the symmetry groups of macromolecular complexes.Hamidreza HeydarianMaarten JoostenAdrian PrzybylskiFlorian SchuederRalf JungmannBen van WerkhovenJan Keller-FindeisenJonas RiesSjoerd StallingaMark BatesBernd RiegerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hamidreza Heydarian Maarten Joosten Adrian Przybylski Florian Schueder Ralf Jungmann Ben van Werkhoven Jan Keller-Findeisen Jonas Ries Sjoerd Stallinga Mark Bates Bernd Rieger 3D particle averaging and detection of macromolecular symmetry in localization microscopy
description	Adaptation of current algorithms to 3D SMLM data is currently problematic. Here the authors report a method that increases the signal-to-noise ratio and resolution of 3D single particle analysis in localization microscopy and enables determination of the symmetry groups of macromolecular complexes.
format	article
author	Hamidreza Heydarian Maarten Joosten Adrian Przybylski Florian Schueder Ralf Jungmann Ben van Werkhoven Jan Keller-Findeisen Jonas Ries Sjoerd Stallinga Mark Bates Bernd Rieger
author_facet	Hamidreza Heydarian Maarten Joosten Adrian Przybylski Florian Schueder Ralf Jungmann Ben van Werkhoven Jan Keller-Findeisen Jonas Ries Sjoerd Stallinga Mark Bates Bernd Rieger
author_sort	Hamidreza Heydarian
title	3D particle averaging and detection of macromolecular symmetry in localization microscopy
title_short	3D particle averaging and detection of macromolecular symmetry in localization microscopy
title_full	3D particle averaging and detection of macromolecular symmetry in localization microscopy
title_fullStr	3D particle averaging and detection of macromolecular symmetry in localization microscopy
title_full_unstemmed	3D particle averaging and detection of macromolecular symmetry in localization microscopy
title_sort	3d particle averaging and detection of macromolecular symmetry in localization microscopy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d17ad19811dd4f2a9819d5862675ea69
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3D particle averaging and detection of macromolecular symmetry in localization microscopy

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