Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis
The bacterial diterpene synthase CotB2 catalyses the cyclisation of geranylgeranyl diphosphate to cyclooctat-9-en7-ol. Here the authors present various CotB2 structures including a trapped abrupt reaction product that were used for molecular dynamic simulations and allowed them to model all intermed...
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Autores principales: | Ronja Driller, Sophie Janke, Monika Fuchs, Evelyn Warner, Anil R. Mhashal, Dan Thomas Major, Mathias Christmann, Thomas Brück, Bernhard Loll |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/d17e467129ff4b9c86987611db040f82 |
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