Accurate quantification of copy-number aberrations and whole-genome duplications in multi-sample tumor sequencing data

The correct identification of copy-number aberrations (CNAs) in tumours can provide information for diagnosis, prognosis and therapeutic strategies. Here, the authors provide an algorithm, HATCHet, which quantifies CNAs using multiple samples from the same patient, providing more accurate informatio...

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Bibliographic Details
Main Authors: Simone Zaccaria, Benjamin J. Raphael
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/d18065c0ce5f4afc9e3938b4dc81d7bd
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