FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN

Objective: To determine the frequency of Kell blood group antigens (K and k) in blood donors from northernPakistan. Study Design: Cross sectional study. Place and Duration of Study: The study was carried out at immunohaematology department of Armed Forces Institute of Transfusion (AFIT) Rawalp...

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Autores principales:	Asad Mehmood, Maqbool Alam, Muhammad Sajid Yazdani, Muhammad Ali Rathore
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	blood donors kell blood group Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d19065b98549428780d6b7961908793a
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spelling	oai:doaj.org-article:d19065b98549428780d6b7961908793a2021-11-09T02:51:19ZFREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN0030-96482411-8842https://doaj.org/article/d19065b98549428780d6b7961908793a2019-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3398/2373https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the frequency of Kell blood group antigens (K and k) in blood donors from northernPakistan. Study Design: Cross sectional study. Place and Duration of Study: The study was carried out at immunohaematology department of Armed Forces Institute of Transfusion (AFIT) Rawalpindi, Pakistan, from 1st Nov 2017 to 31st Dec 2017. Methodology: After approval of Ethical Committee of Armed Forces Institute of Transfusion (AFIT) Rawalpindi, the blood samples of 2000 blood donors were collected. Samples were selected by non-probability consecutive sampling technique. After preliminary blood grouping for ABO and Rh D, these samples were phenotyped for K (kelleher) and k (celleno) antigens. Typing was performed on Biorad® automated blood grouping system by column agglutination technique (CAT), strictly following manufacturer’s instructions. Results: Out of 2000 blood donors, typed for K and k antigens, 1966 were males (98.30%) and 34 were females (1.70%). The frequency of K was 4.05% (81/2000) and that of k was 98.90% (1978/2000). The phenotype K-k+ (95.15%) was most prevalent followed by K+k+ (3.75%), K-k- (0.80%) and K+,k- (0.30%). Conclusion: K antigen frequency is lower than as reported in Caucasions and Saudi Arabia but higher than Indian and African blood donors. This study confirmed that the k (celleno) blood group antigen was highly prevalent antigen in Pakistani population while the K (kelleher) antigen was present in a relatively lower frequency.Asad MehmoodMaqbool AlamMuhammad Sajid YazdaniMuhammad Ali RathoreArmy Medical College Rawalpindiarticleblood donorskell blood groupMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 5, Pp 977-980 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	blood donors kell blood group Medicine R Medicine (General) R5-920
spellingShingle	blood donors kell blood group Medicine R Medicine (General) R5-920 Asad Mehmood Maqbool Alam Muhammad Sajid Yazdani Muhammad Ali Rathore FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN
description	Objective: To determine the frequency of Kell blood group antigens (K and k) in blood donors from northernPakistan. Study Design: Cross sectional study. Place and Duration of Study: The study was carried out at immunohaematology department of Armed Forces Institute of Transfusion (AFIT) Rawalpindi, Pakistan, from 1st Nov 2017 to 31st Dec 2017. Methodology: After approval of Ethical Committee of Armed Forces Institute of Transfusion (AFIT) Rawalpindi, the blood samples of 2000 blood donors were collected. Samples were selected by non-probability consecutive sampling technique. After preliminary blood grouping for ABO and Rh D, these samples were phenotyped for K (kelleher) and k (celleno) antigens. Typing was performed on Biorad® automated blood grouping system by column agglutination technique (CAT), strictly following manufacturer’s instructions. Results: Out of 2000 blood donors, typed for K and k antigens, 1966 were males (98.30%) and 34 were females (1.70%). The frequency of K was 4.05% (81/2000) and that of k was 98.90% (1978/2000). The phenotype K-k+ (95.15%) was most prevalent followed by K+k+ (3.75%), K-k- (0.80%) and K+,k- (0.30%). Conclusion: K antigen frequency is lower than as reported in Caucasions and Saudi Arabia but higher than Indian and African blood donors. This study confirmed that the k (celleno) blood group antigen was highly prevalent antigen in Pakistani population while the K (kelleher) antigen was present in a relatively lower frequency.
format	article
author	Asad Mehmood Maqbool Alam Muhammad Sajid Yazdani Muhammad Ali Rathore
author_facet	Asad Mehmood Maqbool Alam Muhammad Sajid Yazdani Muhammad Ali Rathore
author_sort	Asad Mehmood
title	FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN
title_short	FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN
title_full	FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN
title_fullStr	FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN
title_full_unstemmed	FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN
title_sort	frequency of kell antigens (k & k) among blood donors of northern pakistan
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/d19065b98549428780d6b7961908793a
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FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN

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