Identification of epigenetic memory candidates associated with gestational age at birth through analysis of methylome and transcriptional data

Identification of epigenetic memory candidates associated with gestational age at birth through analysis of methylome and transcriptional data

Abstract Preterm birth is known to be associated with chronic disease risk in adulthood whereby epigenetic memory may play a mechanistic role in disease susceptibility. Gestational age (GA) is the most important prognostic factor for preterm infants, and numerous DNA methylation alterations associat...

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Autores principales: Kohei Kashima, Tomoko Kawai, Riki Nishimura, Yuh Shiwa, Kevin Y. Urayama, Hiromi Kamura, Kazue Takeda, Saki Aoto, Atsushi Ito, Keiko Matsubara, Takeshi Nagamatsu, Tomoyuki Fujii, Isaku Omori, Mitsumasa Shimizu, Hironobu Hyodo, Koji Kugu, Kenji Matsumoto, Atsushi Shimizu, Akira Oka, Masashi Mizuguchi, Kazuhiko Nakabayashi, Kenichiro Hata, Naoto Takahashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d19953f3e7764855b55f244b17ba277f
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