CLEC5A is a critical receptor in innate immunity against Listeria infection

The lectin receptor CLEC5A is a pattern recognition receptor that has been shown to detect dengue and Japanese encephalitis virus. Here the authors show that CLEC5A is needed for optimal ROS production, NET formation and other immune responses to Listeria monocytogenes in mice.

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Autores principales: Szu-Ting Chen, Fei-Ju Li, Tzy-yun Hsu, Shu-Mei Liang, Yi-Chen Yeh, Wen-Yu Liao, Teh-Ying Chou, Nien-Jun Chen, Michael Hsiao, Wen-Bin Yang, Shie-Liang Hsieh
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d19e8915e5a741c68f75e4a20fa992df
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spelling oai:doaj.org-article:d19e8915e5a741c68f75e4a20fa992df2021-12-02T10:48:28ZCLEC5A is a critical receptor in innate immunity against Listeria infection10.1038/s41467-017-00356-32041-1723https://doaj.org/article/d19e8915e5a741c68f75e4a20fa992df2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00356-3https://doaj.org/toc/2041-1723The lectin receptor CLEC5A is a pattern recognition receptor that has been shown to detect dengue and Japanese encephalitis virus. Here the authors show that CLEC5A is needed for optimal ROS production, NET formation and other immune responses to Listeria monocytogenes in mice.Szu-Ting ChenFei-Ju LiTzy-yun HsuShu-Mei LiangYi-Chen YehWen-Yu LiaoTeh-Ying ChouNien-Jun ChenMichael HsiaoWen-Bin YangShie-Liang HsiehNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Szu-Ting Chen
Fei-Ju Li
Tzy-yun Hsu
Shu-Mei Liang
Yi-Chen Yeh
Wen-Yu Liao
Teh-Ying Chou
Nien-Jun Chen
Michael Hsiao
Wen-Bin Yang
Shie-Liang Hsieh
CLEC5A is a critical receptor in innate immunity against Listeria infection
description The lectin receptor CLEC5A is a pattern recognition receptor that has been shown to detect dengue and Japanese encephalitis virus. Here the authors show that CLEC5A is needed for optimal ROS production, NET formation and other immune responses to Listeria monocytogenes in mice.
format article
author Szu-Ting Chen
Fei-Ju Li
Tzy-yun Hsu
Shu-Mei Liang
Yi-Chen Yeh
Wen-Yu Liao
Teh-Ying Chou
Nien-Jun Chen
Michael Hsiao
Wen-Bin Yang
Shie-Liang Hsieh
author_facet Szu-Ting Chen
Fei-Ju Li
Tzy-yun Hsu
Shu-Mei Liang
Yi-Chen Yeh
Wen-Yu Liao
Teh-Ying Chou
Nien-Jun Chen
Michael Hsiao
Wen-Bin Yang
Shie-Liang Hsieh
author_sort Szu-Ting Chen
title CLEC5A is a critical receptor in innate immunity against Listeria infection
title_short CLEC5A is a critical receptor in innate immunity against Listeria infection
title_full CLEC5A is a critical receptor in innate immunity against Listeria infection
title_fullStr CLEC5A is a critical receptor in innate immunity against Listeria infection
title_full_unstemmed CLEC5A is a critical receptor in innate immunity against Listeria infection
title_sort clec5a is a critical receptor in innate immunity against listeria infection
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/d19e8915e5a741c68f75e4a20fa992df
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