Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Uterine leiomyomata (UL) or fibroids are neoplasms of the uterine smooth muscle associated with heavy menstrual bleeding and other female reproductive tract morbidity. Here, the authors identify eight previously undescribed genetic loci for UL and further look into genetic overlap with heavy menstru...

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Autores principales: C. S. Gallagher, N. Mäkinen, H. R. Harris, N. Rahmioglu, O. Uimari, J. P. Cook, N. Shigesi, T. Ferreira, D. R. Velez-Edwards, T. L. Edwards, S. Mortlock, Z. Ruhioglu, F. Day, C. M. Becker, V. Karhunen, H. Martikainen, M.-R. Järvelin, R. M. Cantor, P. M. Ridker, K. L. Terry, J. E. Buring, S. D. Gordon, S. E. Medland, G. W. Montgomery, D. R. Nyholt, D. A. Hinds, J. Y. Tung, the 23andMe Research Team, J. R. B. Perry, P. A. Lind, J. N. Painter, N. G. Martin, A. P. Morris, D. I. Chasman, S. A. Missmer, K. T. Zondervan, C. C. Morton
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d1a4318550c6403d984ad10ede4120c7
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spelling oai:doaj.org-article:d1a4318550c6403d984ad10ede4120c72021-12-02T17:02:17ZGenome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis10.1038/s41467-019-12536-42041-1723https://doaj.org/article/d1a4318550c6403d984ad10ede4120c72019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12536-4https://doaj.org/toc/2041-1723Uterine leiomyomata (UL) or fibroids are neoplasms of the uterine smooth muscle associated with heavy menstrual bleeding and other female reproductive tract morbidity. Here, the authors identify eight previously undescribed genetic loci for UL and further look into genetic overlap with heavy menstrual bleeding and endometriosis.C. S. GallagherN. MäkinenH. R. HarrisN. RahmiogluO. UimariJ. P. CookN. ShigesiT. FerreiraD. R. Velez-EdwardsT. L. EdwardsS. MortlockZ. RuhiogluF. DayC. M. BeckerV. KarhunenH. MartikainenM.-R. JärvelinR. M. CantorP. M. RidkerK. L. TerryJ. E. BuringS. D. GordonS. E. MedlandG. W. MontgomeryD. R. NyholtD. A. HindsJ. Y. Tungthe 23andMe Research TeamJ. R. B. PerryP. A. LindJ. N. PainterN. G. MartinA. P. MorrisD. I. ChasmanS. A. MissmerK. T. ZondervanC. C. MortonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
C. S. Gallagher
N. Mäkinen
H. R. Harris
N. Rahmioglu
O. Uimari
J. P. Cook
N. Shigesi
T. Ferreira
D. R. Velez-Edwards
T. L. Edwards
S. Mortlock
Z. Ruhioglu
F. Day
C. M. Becker
V. Karhunen
H. Martikainen
M.-R. Järvelin
R. M. Cantor
P. M. Ridker
K. L. Terry
J. E. Buring
S. D. Gordon
S. E. Medland
G. W. Montgomery
D. R. Nyholt
D. A. Hinds
J. Y. Tung
the 23andMe Research Team
J. R. B. Perry
P. A. Lind
J. N. Painter
N. G. Martin
A. P. Morris
D. I. Chasman
S. A. Missmer
K. T. Zondervan
C. C. Morton
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
description Uterine leiomyomata (UL) or fibroids are neoplasms of the uterine smooth muscle associated with heavy menstrual bleeding and other female reproductive tract morbidity. Here, the authors identify eight previously undescribed genetic loci for UL and further look into genetic overlap with heavy menstrual bleeding and endometriosis.
format article
author C. S. Gallagher
N. Mäkinen
H. R. Harris
N. Rahmioglu
O. Uimari
J. P. Cook
N. Shigesi
T. Ferreira
D. R. Velez-Edwards
T. L. Edwards
S. Mortlock
Z. Ruhioglu
F. Day
C. M. Becker
V. Karhunen
H. Martikainen
M.-R. Järvelin
R. M. Cantor
P. M. Ridker
K. L. Terry
J. E. Buring
S. D. Gordon
S. E. Medland
G. W. Montgomery
D. R. Nyholt
D. A. Hinds
J. Y. Tung
the 23andMe Research Team
J. R. B. Perry
P. A. Lind
J. N. Painter
N. G. Martin
A. P. Morris
D. I. Chasman
S. A. Missmer
K. T. Zondervan
C. C. Morton
author_facet C. S. Gallagher
N. Mäkinen
H. R. Harris
N. Rahmioglu
O. Uimari
J. P. Cook
N. Shigesi
T. Ferreira
D. R. Velez-Edwards
T. L. Edwards
S. Mortlock
Z. Ruhioglu
F. Day
C. M. Becker
V. Karhunen
H. Martikainen
M.-R. Järvelin
R. M. Cantor
P. M. Ridker
K. L. Terry
J. E. Buring
S. D. Gordon
S. E. Medland
G. W. Montgomery
D. R. Nyholt
D. A. Hinds
J. Y. Tung
the 23andMe Research Team
J. R. B. Perry
P. A. Lind
J. N. Painter
N. G. Martin
A. P. Morris
D. I. Chasman
S. A. Missmer
K. T. Zondervan
C. C. Morton
author_sort C. S. Gallagher
title Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
title_short Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
title_full Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
title_fullStr Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
title_full_unstemmed Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
title_sort genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d1a4318550c6403d984ad10ede4120c7
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