Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs

The range of Hedgehog (Hh) signalling in the Drosophila imaginal disc is limited by Hh/receptor degradation at the anterior/posterior (A/P) compartment boundary. Here, the authors show that degradation is mediated by co-receptor proteins Ihog/Boi, whose cell adhesion functions also contribute to A/P...

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Autores principales:	Elaine Y. C. Hsia, Ya Zhang, Hai Son Tran, Agnes Lim, Ya-Hui Chou, Ganhui Lan, Philip A. Beachy, Xiaoyan Zheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d1ad42630bbe4e7ea6ccabf94efdcf2a
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spelling	oai:doaj.org-article:d1ad42630bbe4e7ea6ccabf94efdcf2a2021-12-02T14:40:36ZHedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs10.1038/s41467-017-01364-z2041-1723https://doaj.org/article/d1ad42630bbe4e7ea6ccabf94efdcf2a2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01364-zhttps://doaj.org/toc/2041-1723The range of Hedgehog (Hh) signalling in the Drosophila imaginal disc is limited by Hh/receptor degradation at the anterior/posterior (A/P) compartment boundary. Here, the authors show that degradation is mediated by co-receptor proteins Ihog/Boi, whose cell adhesion functions also contribute to A/P cell segregation.Elaine Y. C. HsiaYa ZhangHai Son TranAgnes LimYa-Hui ChouGanhui LanPhilip A. BeachyXiaoyan ZhengNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elaine Y. C. Hsia Ya Zhang Hai Son Tran Agnes Lim Ya-Hui Chou Ganhui Lan Philip A. Beachy Xiaoyan Zheng Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
description	The range of Hedgehog (Hh) signalling in the Drosophila imaginal disc is limited by Hh/receptor degradation at the anterior/posterior (A/P) compartment boundary. Here, the authors show that degradation is mediated by co-receptor proteins Ihog/Boi, whose cell adhesion functions also contribute to A/P cell segregation.
format	article
author	Elaine Y. C. Hsia Ya Zhang Hai Son Tran Agnes Lim Ya-Hui Chou Ganhui Lan Philip A. Beachy Xiaoyan Zheng
author_facet	Elaine Y. C. Hsia Ya Zhang Hai Son Tran Agnes Lim Ya-Hui Chou Ganhui Lan Philip A. Beachy Xiaoyan Zheng
author_sort	Elaine Y. C. Hsia
title	Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
title_short	Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
title_full	Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
title_fullStr	Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
title_full_unstemmed	Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
title_sort	hedgehog mediated degradation of ihog adhesion proteins modulates cell segregation in drosophila wing imaginal discs
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d1ad42630bbe4e7ea6ccabf94efdcf2a
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Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs

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