Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study

Abstract We aimed to investigate the association between carotid plaques and cognitive impairment among patients with acute ischemic stroke, and to assess key clinical implications. In the Acute Ischemic Stroke Study, patients who received a cognitive testing and underwent complete carotid artery ul...

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Autores principales:	Anxin Wang, Xiaoxue Liu, Guojuan Chen, Hongjun Hao, Yongjun Wang, Yilong Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d1b2d9625fd04cafa4da7504c3f2cfcb
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spelling	oai:doaj.org-article:d1b2d9625fd04cafa4da7504c3f2cfcb2021-12-02T11:40:15ZAssociation between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study10.1038/s41598-017-02435-32045-2322https://doaj.org/article/d1b2d9625fd04cafa4da7504c3f2cfcb2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02435-3https://doaj.org/toc/2045-2322Abstract We aimed to investigate the association between carotid plaques and cognitive impairment among patients with acute ischemic stroke, and to assess key clinical implications. In the Acute Ischemic Stroke Study, patients who received a cognitive testing and underwent complete carotid artery ultrasound scans were included. Cognitive function was measured by the mini-mental state examination. The cross-sectional relationships between cognitive impairment and carotid plaques were evaluated using multivariate logistic regression analysis. Of the 3116 patients included in this study, 826 (26.51%) patients were diagnosed with cognitive impairment. After adjusting for potential confounders, patients with ≥2 carotid plaques (odds ratio [OR] = 1.47; 95% confidence interval [CI]: 1.19–1.82), patients with ≥2 number of carotid arteries with plaque (OR = 1.48; 95% CI: 1.19–1.84) and patients with hypoechoic plaque (OR = 2.05; 95% CI: 1.24–3.38) are more likely to have cognitive impairment. In this acute ischemic stroke population, the number of carotid plaques, the number of carotid arteries with plaque and plaque stability are all associated with cognitive impairment.Anxin WangXiaoxue LiuGuojuan ChenHongjun HaoYongjun WangYilong WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Anxin Wang Xiaoxue Liu Guojuan Chen Hongjun Hao Yongjun Wang Yilong Wang Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study
description	Abstract We aimed to investigate the association between carotid plaques and cognitive impairment among patients with acute ischemic stroke, and to assess key clinical implications. In the Acute Ischemic Stroke Study, patients who received a cognitive testing and underwent complete carotid artery ultrasound scans were included. Cognitive function was measured by the mini-mental state examination. The cross-sectional relationships between cognitive impairment and carotid plaques were evaluated using multivariate logistic regression analysis. Of the 3116 patients included in this study, 826 (26.51%) patients were diagnosed with cognitive impairment. After adjusting for potential confounders, patients with ≥2 carotid plaques (odds ratio [OR] = 1.47; 95% confidence interval [CI]: 1.19–1.82), patients with ≥2 number of carotid arteries with plaque (OR = 1.48; 95% CI: 1.19–1.84) and patients with hypoechoic plaque (OR = 2.05; 95% CI: 1.24–3.38) are more likely to have cognitive impairment. In this acute ischemic stroke population, the number of carotid plaques, the number of carotid arteries with plaque and plaque stability are all associated with cognitive impairment.
format	article
author	Anxin Wang Xiaoxue Liu Guojuan Chen Hongjun Hao Yongjun Wang Yilong Wang
author_facet	Anxin Wang Xiaoxue Liu Guojuan Chen Hongjun Hao Yongjun Wang Yilong Wang
author_sort	Anxin Wang
title	Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study
title_short	Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study
title_full	Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study
title_fullStr	Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study
title_full_unstemmed	Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study
title_sort	association between carotid plaque and cognitive impairment in chinese stroke population: the sos-stroke study
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d1b2d9625fd04cafa4da7504c3f2cfcb
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Association between Carotid Plaque and Cognitive Impairment in Chinese Stroke Population: The SOS-Stroke Study

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