Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress
Cyclins A2 and E1 are known to regulate the cell cycle by promoting S phase entry and progression. Here, they identify an aggressive hepatocellular carcinoma subgroup exhibiting cyclin activation through various mechanisms and find this subgroup to display replication stress-induced structural rearr...
Guardado en:
Autores principales: | Quentin Bayard, Léa Meunier, Camille Peneau, Victor Renault, Jayendra Shinde, Jean-Charles Nault, Iadh Mami, Gabrielle Couchy, Giuliana Amaddeo, Emmanuel Tubacher, Delphine Bacq, Vincent Meyer, Tiziana La Bella, Audrey Debaillon-Vesque, Paulette Bioulac-Sage, Olivier Seror, Jean-Frédéric Blanc, Julien Calderaro, Jean-François Deleuze, Sandrine Imbeaud, Jessica Zucman-Rossi, Eric Letouzé |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d1c71c5d3832437783153fd87d02ea45 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
por: Eric Letouzé, et al.
Publicado: (2017) -
Genomic characterization of rare molecular subclasses of hepatocellular carcinoma
por: Jeffrey S. Damrauer, et al.
Publicado: (2021) -
CONCENTRATIONS OF IgG SUBCLASSES IN ALLOGENEIC BONE MARROW RECIPIENTS
por: A. V. Klimovich, et al.
Publicado: (2014) -
Study on Certain Subclass of Analytic Functions Involving Mittag-Leffler Function
por: Nazek Alessa, et al.
Publicado: (2021) -
A certain subclass of uniformly convex functions defined by Bessel functions
por: Thirupathi Reddy,P., et al.
Publicado: (2019)