Audio-Vestibular Findings in Patients with Hyperuricemia

Background: Hyperuricemiais a common biochemical disturbance in which serum concentration of uric acid exceeds the normal values which is 7.0 mg/dl in men and more than 6.0 mg/dl in women leading to deposition of monosodium urate [MSU] crystals in joints and soft tissues resulting in inner ear funct...

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Autores principales:	Mohamed Mahmoud Al-Sobki, Gehan Abd-Al-Rahman El-Zarea, Ahmed Mohamed Ahmed Mahmoud, Ahmed Abd El Moez Ali Saad
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	audio-vestibular sensorineural hearing loss vertigo hyperuricemia, uric acid Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d1c7ffaa25b94cf598d222f2c9f21f43
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spelling	oai:doaj.org-article:d1c7ffaa25b94cf598d222f2c9f21f432021-12-02T13:52:45ZAudio-Vestibular Findings in Patients with Hyperuricemia2636-41742682-378010.21608/ijma.2020.38516.1153https://doaj.org/article/d1c7ffaa25b94cf598d222f2c9f21f432020-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_117260_4f5326519dc4aef1ae32d96d12bf60a6.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Hyperuricemiais a common biochemical disturbance in which serum concentration of uric acid exceeds the normal values which is 7.0 mg/dl in men and more than 6.0 mg/dl in women leading to deposition of monosodium urate [MSU] crystals in joints and soft tissues resulting in inner ear functions affection. Aim of the work: To elaborate the effect of hyperuricemia on the peripheral hearing as well as peripheral vestibular functions. Subjects and Methods: This study included 40 subjects with hyperuricemia and 40 healthy controls. Participants underwent serum uric acid assay, full history taking, basic audiological evaluation and vestibular evaluation. Results: 37[92.5%] hyperuricemic subjects had normal peripheral hearing sensitivity, only 3[7.5%] had mild high frequencies sensori-neural hearing loss [SNHL] at 8 kHz. 31[77.5%] Hyperuricemic patients had normal peripheral vestibular functions, only 9[22.5%] subjects had BPPV; They also had higher serum uric acid [SUA] level. No correlation between duration of hyperuricemia and occurrence of BPPV. Conclusions: The hyperuricemic subjects had a significant higher incidence of BPPV. Other investigations to detect early and subtle changes in cochlear function of hyperuricemic subjects were recommended.Mohamed Mahmoud Al-SobkiGehan Abd-Al-Rahman El-ZareaAhmed Mohamed Ahmed MahmoudAhmed Abd El Moez Ali SaadAl-Azhar University, Faculty of Medicine (Damietta)articleaudio-vestibularsensorineural hearing lossvertigohyperuricemia, uric acidMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 4, Pp 866-872 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	audio-vestibular sensorineural hearing loss vertigo hyperuricemia, uric acid Medicine (General) R5-920
spellingShingle	audio-vestibular sensorineural hearing loss vertigo hyperuricemia, uric acid Medicine (General) R5-920 Mohamed Mahmoud Al-Sobki Gehan Abd-Al-Rahman El-Zarea Ahmed Mohamed Ahmed Mahmoud Ahmed Abd El Moez Ali Saad Audio-Vestibular Findings in Patients with Hyperuricemia
description	Background: Hyperuricemiais a common biochemical disturbance in which serum concentration of uric acid exceeds the normal values which is 7.0 mg/dl in men and more than 6.0 mg/dl in women leading to deposition of monosodium urate [MSU] crystals in joints and soft tissues resulting in inner ear functions affection. Aim of the work: To elaborate the effect of hyperuricemia on the peripheral hearing as well as peripheral vestibular functions. Subjects and Methods: This study included 40 subjects with hyperuricemia and 40 healthy controls. Participants underwent serum uric acid assay, full history taking, basic audiological evaluation and vestibular evaluation. Results: 37[92.5%] hyperuricemic subjects had normal peripheral hearing sensitivity, only 3[7.5%] had mild high frequencies sensori-neural hearing loss [SNHL] at 8 kHz. 31[77.5%] Hyperuricemic patients had normal peripheral vestibular functions, only 9[22.5%] subjects had BPPV; They also had higher serum uric acid [SUA] level. No correlation between duration of hyperuricemia and occurrence of BPPV. Conclusions: The hyperuricemic subjects had a significant higher incidence of BPPV. Other investigations to detect early and subtle changes in cochlear function of hyperuricemic subjects were recommended.
format	article
author	Mohamed Mahmoud Al-Sobki Gehan Abd-Al-Rahman El-Zarea Ahmed Mohamed Ahmed Mahmoud Ahmed Abd El Moez Ali Saad
author_facet	Mohamed Mahmoud Al-Sobki Gehan Abd-Al-Rahman El-Zarea Ahmed Mohamed Ahmed Mahmoud Ahmed Abd El Moez Ali Saad
author_sort	Mohamed Mahmoud Al-Sobki
title	Audio-Vestibular Findings in Patients with Hyperuricemia
title_short	Audio-Vestibular Findings in Patients with Hyperuricemia
title_full	Audio-Vestibular Findings in Patients with Hyperuricemia
title_fullStr	Audio-Vestibular Findings in Patients with Hyperuricemia
title_full_unstemmed	Audio-Vestibular Findings in Patients with Hyperuricemia
title_sort	audio-vestibular findings in patients with hyperuricemia
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/d1c7ffaa25b94cf598d222f2c9f21f43
work_keys_str_mv	AT mohamedmahmoudalsobki audiovestibularfindingsinpatientswithhyperuricemia AT gehanabdalrahmanelzarea audiovestibularfindingsinpatientswithhyperuricemia AT ahmedmohamedahmedmahmoud audiovestibularfindingsinpatientswithhyperuricemia AT ahmedabdelmoezalisaad audiovestibularfindingsinpatientswithhyperuricemia
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Audio-Vestibular Findings in Patients with Hyperuricemia

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