Adaptive versus maladaptive cardiac remodelling in response to sustained β-adrenergic stimulation in a new 'ISO on/off model'.

On the one hand, sustained β-adrenergic stress is a hallmark of heart failure (HF) and exerts maladaptive cardiac remodelling. On the other hand, acute β-adrenergic stimulation maintains cardiac function under physiological stress. However, it is still incompletely understood to what extent the adap...

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Autores principales: Stefanie Maria Werhahn, Julia S Kreusser, Marco Hagenmüller, Jan Beckendorf, Nathalie Diemert, Sophia Hoffmann, Jobst-Hendrik Schultz, Johannes Backs, Matthias Dewenter
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/d1d8f811b1ec4d189016d694d9b39855
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