Adaptive versus maladaptive cardiac remodelling in response to sustained β-adrenergic stimulation in a new 'ISO on/off model'.
On the one hand, sustained β-adrenergic stress is a hallmark of heart failure (HF) and exerts maladaptive cardiac remodelling. On the other hand, acute β-adrenergic stimulation maintains cardiac function under physiological stress. However, it is still incompletely understood to what extent the adap...
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Autores principales: | Stefanie Maria Werhahn, Julia S Kreusser, Marco Hagenmüller, Jan Beckendorf, Nathalie Diemert, Sophia Hoffmann, Jobst-Hendrik Schultz, Johannes Backs, Matthias Dewenter |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d1d8f811b1ec4d189016d694d9b39855 |
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