Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing

Aberrant tissue repair may result in heterotopic ossification (HO), but how this process is regulated by local inflammatory responses is still unclear. Here the authors show, using a mouse burn/trauma model, that TGFβ-producing monocytes/macrophages at the injury site contribute to HO induction, whi...

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Autores principales: Michael Sorkin, Amanda K. Huber, Charles Hwang, William F. Carson, Rajasree Menon, John Li, Kaetlin Vasquez, Chase Pagani, Nicole Patel, Shuli Li, Noelle D. Visser, Yashar Niknafs, Shawn Loder, Melissa Scola, Dylan Nycz, Katherine Gallagher, Laurie K. McCauley, Jiajia Xu, Aaron W. James, Shailesh Agarwal, Stephen Kunkel, Yuji Mishina, Benjamin Levi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d1da08c830104fc9b81a6525ff7ff86b
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