EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING

The study included thirty-one patients with coronary heart disease before the procedure of percutaneous transluminal coronary angioplasty with stenting and the day after the surgery. Flow cytometric assays were performed in order to determine major subpopulations of peripheral lymphocytes (CD3+CD19-...

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Autores principales:	O. S. Shkoda, A. N. Shilova, V. S. Kozyreva, A. M. Chernyavsky
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2016
Materias:	coronary artery disease surgery flow cytometry immune profile Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/d1f421c89dd94b12b869a5693d8b3f54
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spelling	oai:doaj.org-article:d1f421c89dd94b12b869a5693d8b3f542021-11-18T08:03:45ZEVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING1563-06252313-741X10.15789/1563-0625-2016-2-171-176https://doaj.org/article/d1f421c89dd94b12b869a5693d8b3f542016-04-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1000https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe study included thirty-one patients with coronary heart disease before the procedure of percutaneous transluminal coronary angioplasty with stenting and the day after the surgery. Flow cytometric assays were performed in order to determine major subpopulations of peripheral lymphocytes (CD3+CD19- , CD3- CD19+, CD3- CD16+CD56+, CD3+CD16+CD56+). A statistically significant decrease in the relative amount of total T-lymphocytes and increased relative content of NK and NK-T-cells was revealed in the patients under study when compared with healthy donors. The decrease in CD3+CD19- subpopulation did correlate with increased CD3- CD16+CD56+ lymphocyte set. We have not found any significant changes of immune profile at the early terms post-surgery, when compared with appropriate results obtained pre-surgery.O. S. ShkodaA. N. ShilovaV. S. KozyrevaA. M. ChernyavskySPb RAACIarticlecoronary artery diseasesurgeryflow cytometryimmune profileImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 18, Iss 2, Pp 171-176 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	coronary artery disease surgery flow cytometry immune profile Immunologic diseases. Allergy RC581-607
spellingShingle	coronary artery disease surgery flow cytometry immune profile Immunologic diseases. Allergy RC581-607 O. S. Shkoda A. N. Shilova V. S. Kozyreva A. M. Chernyavsky EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING
description	The study included thirty-one patients with coronary heart disease before the procedure of percutaneous transluminal coronary angioplasty with stenting and the day after the surgery. Flow cytometric assays were performed in order to determine major subpopulations of peripheral lymphocytes (CD3+CD19- , CD3- CD19+, CD3- CD16+CD56+, CD3+CD16+CD56+). A statistically significant decrease in the relative amount of total T-lymphocytes and increased relative content of NK and NK-T-cells was revealed in the patients under study when compared with healthy donors. The decrease in CD3+CD19- subpopulation did correlate with increased CD3- CD16+CD56+ lymphocyte set. We have not found any significant changes of immune profile at the early terms post-surgery, when compared with appropriate results obtained pre-surgery.
format	article
author	O. S. Shkoda A. N. Shilova V. S. Kozyreva A. M. Chernyavsky
author_facet	O. S. Shkoda A. N. Shilova V. S. Kozyreva A. M. Chernyavsky
author_sort	O. S. Shkoda
title	EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING
title_short	EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING
title_full	EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING
title_fullStr	EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING
title_full_unstemmed	EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING
title_sort	evaluation of main indexes of immune state in the patients with percutaneous transluminal coronary angioplasty with stenting
publisher	SPb RAACI
publishDate	2016
url	https://doaj.org/article/d1f421c89dd94b12b869a5693d8b3f54
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EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING

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