Relacin, a novel antibacterial agent targeting the Stringent Response.
Finding bacterial cellular targets for developing novel antibiotics has become a major challenge in fighting resistant pathogenic bacteria. We present a novel compound, Relacin, designed to inhibit (p)ppGpp production by the ubiquitous bacterial enzyme RelA that triggers the Stringent Response. Rela...
Enregistré dans:
Auteurs principaux: | Ezequiel Wexselblatt, Yaara Oppenheimer-Shaanan, Ilana Kaspy, Nir London, Ora Schueler-Furman, Eylon Yavin, Gad Glaser, Joshua Katzhendler, Sigal Ben-Yehuda |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/d1f6e73e68eb43c99e4dd57e26c58e24 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors.
par: Barak Raveh, et autres
Publié: (2011) -
Rapid sampling of molecular motions with prior information constraints.
par: Barak Raveh, et autres
Publié: (2009) -
<named-content content-type="genus-species">Escherichia coli</named-content> Quorum-Sensing EDF, A Peptide Generated by Novel Multiple Distinct Mechanisms and Regulated by <italic toggle="yes">trans</italic>-Translation
par: Sathish Kumar, et autres
Publié: (2016) -
Correction for Kumar et al., “Escherichia coli Quorum-Sensing EDF, A Peptide Generated by Novel Multiple Distinct Mechanisms and Regulated by
<i>trans</i>
-Translation”
par: Sathish Kumar, et autres
Publié: (2021) -
Stringent Response in Mycobacteria: From Biology to Therapeutic Potential
par: Kuldeepkumar Ramnaresh Gupta, et autres
Publié: (2021)