A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis

Here, the authors report the results of a randomized, placebo controlled trial of children with acute gastroenteritis who were treated with a probiotic and find no virus-specific beneficial effects attributable to the probiotic, either in reducing clinical symptoms or clearance of viral nucleic acid...

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Autores principales: Stephen B. Freedman, Jianling Xie, Alberto Nettel-Aguirre, Xiao-Li Pang, Linda Chui, Sarah Williamson-Urquhart, David Schnadower, Suzanne Schuh, Philip M. Sherman, Bonita E. Lee, Serge Gouin, Ken J. Farion, Naveen Poonai, Katrina F. Hurley, Yuanyuan Qiu, Binal Ghandi, Colin Lloyd, Yaron Finkelstein, the Pediatric Emergency Research Canada Probiotic (PERC) Regimen for Outpatient Gastroenteritis Utility of Treatment (PROGUT) Trial Group
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d206e18a36404fdb969e04e767ebc407
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spelling oai:doaj.org-article:d206e18a36404fdb969e04e767ebc4072021-12-02T14:58:51ZA randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis10.1038/s41467-020-16308-32041-1723https://doaj.org/article/d206e18a36404fdb969e04e767ebc4072020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16308-3https://doaj.org/toc/2041-1723Here, the authors report the results of a randomized, placebo controlled trial of children with acute gastroenteritis who were treated with a probiotic and find no virus-specific beneficial effects attributable to the probiotic, either in reducing clinical symptoms or clearance of viral nucleic acid from stool specimens.Stephen B. FreedmanJianling XieAlberto Nettel-AguirreXiao-Li PangLinda ChuiSarah Williamson-UrquhartDavid SchnadowerSuzanne SchuhPhilip M. ShermanBonita E. LeeSerge GouinKen J. FarionNaveen PoonaiKatrina F. HurleyYuanyuan QiuBinal GhandiColin LloydYaron Finkelsteinthe Pediatric Emergency Research Canada Probiotic (PERC) Regimen for Outpatient Gastroenteritis Utility of Treatment (PROGUT) Trial GroupNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stephen B. Freedman
Jianling Xie
Alberto Nettel-Aguirre
Xiao-Li Pang
Linda Chui
Sarah Williamson-Urquhart
David Schnadower
Suzanne Schuh
Philip M. Sherman
Bonita E. Lee
Serge Gouin
Ken J. Farion
Naveen Poonai
Katrina F. Hurley
Yuanyuan Qiu
Binal Ghandi
Colin Lloyd
Yaron Finkelstein
the Pediatric Emergency Research Canada Probiotic (PERC) Regimen for Outpatient Gastroenteritis Utility of Treatment (PROGUT) Trial Group
A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
description Here, the authors report the results of a randomized, placebo controlled trial of children with acute gastroenteritis who were treated with a probiotic and find no virus-specific beneficial effects attributable to the probiotic, either in reducing clinical symptoms or clearance of viral nucleic acid from stool specimens.
format article
author Stephen B. Freedman
Jianling Xie
Alberto Nettel-Aguirre
Xiao-Li Pang
Linda Chui
Sarah Williamson-Urquhart
David Schnadower
Suzanne Schuh
Philip M. Sherman
Bonita E. Lee
Serge Gouin
Ken J. Farion
Naveen Poonai
Katrina F. Hurley
Yuanyuan Qiu
Binal Ghandi
Colin Lloyd
Yaron Finkelstein
the Pediatric Emergency Research Canada Probiotic (PERC) Regimen for Outpatient Gastroenteritis Utility of Treatment (PROGUT) Trial Group
author_facet Stephen B. Freedman
Jianling Xie
Alberto Nettel-Aguirre
Xiao-Li Pang
Linda Chui
Sarah Williamson-Urquhart
David Schnadower
Suzanne Schuh
Philip M. Sherman
Bonita E. Lee
Serge Gouin
Ken J. Farion
Naveen Poonai
Katrina F. Hurley
Yuanyuan Qiu
Binal Ghandi
Colin Lloyd
Yaron Finkelstein
the Pediatric Emergency Research Canada Probiotic (PERC) Regimen for Outpatient Gastroenteritis Utility of Treatment (PROGUT) Trial Group
author_sort Stephen B. Freedman
title A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
title_short A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
title_full A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
title_fullStr A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
title_full_unstemmed A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
title_sort randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d206e18a36404fdb969e04e767ebc407
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