Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes
There are dynamic interactions between immune cells and β cells that lead to β cell destruction in the context of autoimmune diabetes. Here the authors show that TET2, a methylcytosine dioxygenase, can regulate this interaction and deletion of TET2 can prevent the autoimmune destruction of β cells i...
Guardado en:
Autores principales: | Jinxiu Rui, Songyan Deng, Ana Luisa Perdigoto, Gerald Ponath, Romy Kursawe, Nathan Lawlor, Tomokazu Sumida, Maya Levine-Ritterman, Michael L. Stitzel, David Pitt, Jun Lu, Kevan C. Herold |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d2099481cf7c45539fc5dd7688d09511 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis
por: Gerald Ponath, et al.
Publicado: (2018) -
Loss of TET2 and TET3 in regulatory T cells unleashes effector function
por: Xiaojing Yue, et al.
Publicado: (2019) -
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice
por: Eleonora Ottina, et al.
Publicado: (2017) -
Pleonastic tet in the Lapscheure dialect
por: Liliane Haegeman, et al.
Publicado: (2008) -
CHARACTERISTICS OF AUTOIMMUNE INFLAMMATION IN THE PATIENTS WITH LUNG TUBERCULOSIS
por: A. A. Starshinova, et al.
Publicado: (2019)