Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes

There are dynamic interactions between immune cells and β cells that lead to β cell destruction in the context of autoimmune diabetes. Here the authors show that TET2, a methylcytosine dioxygenase, can regulate this interaction and deletion of TET2 can prevent the autoimmune destruction of β cells i...

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Main Authors: Jinxiu Rui, Songyan Deng, Ana Luisa Perdigoto, Gerald Ponath, Romy Kursawe, Nathan Lawlor, Tomokazu Sumida, Maya Levine-Ritterman, Michael L. Stitzel, David Pitt, Jun Lu, Kevan C. Herold
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/d2099481cf7c45539fc5dd7688d09511
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