Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients
Abstract Bronchiolitis manifests as a variety of histological features that explain the complex clinical profiles and imaging aspects. In the period between January 2011 and June 2015, patients with a cryobiopsy diagnosis of bronchiolitis were retrospectively retrieved from the database of our insti...
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oai:doaj.org-article:d2122988bc534968b33737a1649b37aa2021-12-02T18:18:50ZCryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients10.1038/s41598-020-67938-y2045-2322https://doaj.org/article/d2122988bc534968b33737a1649b37aa2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-67938-yhttps://doaj.org/toc/2045-2322Abstract Bronchiolitis manifests as a variety of histological features that explain the complex clinical profiles and imaging aspects. In the period between January 2011 and June 2015, patients with a cryobiopsy diagnosis of bronchiolitis were retrospectively retrieved from the database of our institution. Clinical profiles, imaging features and histologic diagnoses were analysed to identify the role of cryobiopsy in the diagnostic process. Twenty-three patients with a multidisciplinary diagnosis of small airway disease were retrieved (14 females, 9 males; age range 31–74 years old; mean age 54.2 years old). The final MDT diagnoses were post-infectious bronchiolitis (n = 5), constrictive bronchiolitis (n = 3), DIPNECH (n = 1), idiopathic follicular bronchiolitis (n = 3), Sjogren’s disease (n = 1), GLILD (n = 1), smoking-related interstitial lung disease (n = 6), sarcoid with granulomatous bronchiolar disorder (n = 1), and subacute hypersensitivity pneumonitis (n = 2). Complications reported after the cryobiopsy procedure consisted of two cases of pneumothorax soon after the biopsy (8.7%), which were successfully managed with the insertion of a chest tube. Transbronchial cryobiopsy represents a robust and mini-invasive method in the characterization of small airway diseases, allowing a low percentage of complications and good diagnostic confidence.Syakirin Sirol Aflah SyazatulSara PiciucchiSara TomassettiClaudia RavagliaAlessandra DubiniVenerino PolettiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-8 (2020) |
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Medicine R Science Q Syakirin Sirol Aflah Syazatul Sara Piciucchi Sara Tomassetti Claudia Ravaglia Alessandra Dubini Venerino Poletti Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
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Abstract Bronchiolitis manifests as a variety of histological features that explain the complex clinical profiles and imaging aspects. In the period between January 2011 and June 2015, patients with a cryobiopsy diagnosis of bronchiolitis were retrospectively retrieved from the database of our institution. Clinical profiles, imaging features and histologic diagnoses were analysed to identify the role of cryobiopsy in the diagnostic process. Twenty-three patients with a multidisciplinary diagnosis of small airway disease were retrieved (14 females, 9 males; age range 31–74 years old; mean age 54.2 years old). The final MDT diagnoses were post-infectious bronchiolitis (n = 5), constrictive bronchiolitis (n = 3), DIPNECH (n = 1), idiopathic follicular bronchiolitis (n = 3), Sjogren’s disease (n = 1), GLILD (n = 1), smoking-related interstitial lung disease (n = 6), sarcoid with granulomatous bronchiolar disorder (n = 1), and subacute hypersensitivity pneumonitis (n = 2). Complications reported after the cryobiopsy procedure consisted of two cases of pneumothorax soon after the biopsy (8.7%), which were successfully managed with the insertion of a chest tube. Transbronchial cryobiopsy represents a robust and mini-invasive method in the characterization of small airway diseases, allowing a low percentage of complications and good diagnostic confidence. |
format |
article |
author |
Syakirin Sirol Aflah Syazatul Sara Piciucchi Sara Tomassetti Claudia Ravaglia Alessandra Dubini Venerino Poletti |
author_facet |
Syakirin Sirol Aflah Syazatul Sara Piciucchi Sara Tomassetti Claudia Ravaglia Alessandra Dubini Venerino Poletti |
author_sort |
Syakirin Sirol Aflah Syazatul |
title |
Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
title_short |
Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
title_full |
Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
title_fullStr |
Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
title_full_unstemmed |
Cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
title_sort |
cryobiopsy in the diagnosis of bronchiolitis: a retrospective analysis of twenty-three consecutive patients |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/d2122988bc534968b33737a1649b37aa |
work_keys_str_mv |
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