The Agr-Like Quorum-Sensing System Is Important for <italic toggle="yes">Clostridium perfringens</italic> Type A Strain ATCC 3624 To Cause Gas Gangrene in a Mouse Model

ABSTRACT Clostridium perfringens type A is involved in gas gangrene in humans and animals. Following a traumatic injury, rapid bacterial proliferation and exotoxin production result in severe myonecrosis. C. perfringens alpha toxin (CPA) and perfringolysin (PFO) are the main virulence factors respon...

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Autores principales: Mauricio A. Navarro, Jihong Li, Juliann Beingesser, Bruce A. McClane, Francisco A. Uzal
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/d2135dc2b1984eb49ba716bdbefe07e4
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