Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes

Local mechanical properties are important to cellular function; but conventional measurement techniques are limited in intact, living, 3D tissues. Here, the authors report on swellable hydrogel microparticles to monitor mechanical properties in situ via a temperature change.

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Autores principales:	Stephanie Mok, Sara Al Habyan, Charles Ledoux, Wontae Lee, Katherine N. MacDonald, Luke McCaffrey, Christopher Moraes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d218733b67634f729d80644e961dd6ce
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spelling	oai:doaj.org-article:d218733b67634f729d80644e961dd6ce2021-12-02T15:15:24ZMapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes10.1038/s41467-020-18469-72041-1723https://doaj.org/article/d218733b67634f729d80644e961dd6ce2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18469-7https://doaj.org/toc/2041-1723Local mechanical properties are important to cellular function; but conventional measurement techniques are limited in intact, living, 3D tissues. Here, the authors report on swellable hydrogel microparticles to monitor mechanical properties in situ via a temperature change.Stephanie MokSara Al HabyanCharles LedouxWontae LeeKatherine N. MacDonaldLuke McCaffreyChristopher MoraesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephanie Mok Sara Al Habyan Charles Ledoux Wontae Lee Katherine N. MacDonald Luke McCaffrey Christopher Moraes Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes
description	Local mechanical properties are important to cellular function; but conventional measurement techniques are limited in intact, living, 3D tissues. Here, the authors report on swellable hydrogel microparticles to monitor mechanical properties in situ via a temperature change.
format	article
author	Stephanie Mok Sara Al Habyan Charles Ledoux Wontae Lee Katherine N. MacDonald Luke McCaffrey Christopher Moraes
author_facet	Stephanie Mok Sara Al Habyan Charles Ledoux Wontae Lee Katherine N. MacDonald Luke McCaffrey Christopher Moraes
author_sort	Stephanie Mok
title	Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes
title_short	Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes
title_full	Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes
title_fullStr	Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes
title_full_unstemmed	Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes
title_sort	mapping cellular-scale internal mechanics in 3d tissues with thermally responsive hydrogel probes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d218733b67634f729d80644e961dd6ce
work_keys_str_mv	AT stephaniemok mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes AT saraalhabyan mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes AT charlesledoux mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes AT wontaelee mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes AT katherinenmacdonald mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes AT lukemccaffrey mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes AT christophermoraes mappingcellularscaleinternalmechanicsin3dtissueswiththermallyresponsivehydrogelprobes
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Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes

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