Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli

Bacteria must adapt their metabolism in the face of dynamically changing nutrient availability. Here, using their constraint-based modeling approach the authors analyze E. coli exometabolome data during growth in complex medium, revealing temporal coordination of glucose and amino acid catabolism.

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Detalles Bibliográficos
Autores principales: Mattia Zampieri, Manuel Hörl, Florian Hotz, Nicola F. Müller, Uwe Sauer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d228cba1a35142dcaf2eb5c39db5dbe0
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Sumario:Bacteria must adapt their metabolism in the face of dynamically changing nutrient availability. Here, using their constraint-based modeling approach the authors analyze E. coli exometabolome data during growth in complex medium, revealing temporal coordination of glucose and amino acid catabolism.