Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli

Bacteria must adapt their metabolism in the face of dynamically changing nutrient availability. Here, using their constraint-based modeling approach the authors analyze E. coli exometabolome data during growth in complex medium, revealing temporal coordination of glucose and amino acid catabolism.

Guardado en:

Detalles Bibliográficos
Autores principales:	Mattia Zampieri, Manuel Hörl, Florian Hotz, Nicola F. Müller, Uwe Sauer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d228cba1a35142dcaf2eb5c39db5dbe0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d228cba1a35142dcaf2eb5c39db5dbe0
record_format	dspace
spelling	oai:doaj.org-article:d228cba1a35142dcaf2eb5c39db5dbe02021-12-02T17:01:38ZRegulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli10.1038/s41467-019-11331-52041-1723https://doaj.org/article/d228cba1a35142dcaf2eb5c39db5dbe02019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11331-5https://doaj.org/toc/2041-1723Bacteria must adapt their metabolism in the face of dynamically changing nutrient availability. Here, using their constraint-based modeling approach the authors analyze E. coli exometabolome data during growth in complex medium, revealing temporal coordination of glucose and amino acid catabolism.Mattia ZampieriManuel HörlFlorian HotzNicola F. MüllerUwe SauerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mattia Zampieri Manuel Hörl Florian Hotz Nicola F. Müller Uwe Sauer Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
description	Bacteria must adapt their metabolism in the face of dynamically changing nutrient availability. Here, using their constraint-based modeling approach the authors analyze E. coli exometabolome data during growth in complex medium, revealing temporal coordination of glucose and amino acid catabolism.
format	article
author	Mattia Zampieri Manuel Hörl Florian Hotz Nicola F. Müller Uwe Sauer
author_facet	Mattia Zampieri Manuel Hörl Florian Hotz Nicola F. Müller Uwe Sauer
author_sort	Mattia Zampieri
title	Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
title_short	Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
title_full	Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
title_fullStr	Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
title_full_unstemmed	Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
title_sort	regulatory mechanisms underlying coordination of amino acid and glucose catabolism in escherichia coli
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d228cba1a35142dcaf2eb5c39db5dbe0
work_keys_str_mv	AT mattiazampieri regulatorymechanismsunderlyingcoordinationofaminoacidandglucosecatabolisminescherichiacoli AT manuelhorl regulatorymechanismsunderlyingcoordinationofaminoacidandglucosecatabolisminescherichiacoli AT florianhotz regulatorymechanismsunderlyingcoordinationofaminoacidandglucosecatabolisminescherichiacoli AT nicolafmuller regulatorymechanismsunderlyingcoordinationofaminoacidandglucosecatabolisminescherichiacoli AT uwesauer regulatorymechanismsunderlyingcoordinationofaminoacidandglucosecatabolisminescherichiacoli
_version_	1718382114879045632

Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli

Ejemplares similares