Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients

Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients

The distinct genomic and epidemiological features of Chinese lung cancer patients suggest the presence of alternative causal mechanisms. Here, the authors present the genomic landscape of 149 Chinese NSCLC patients and reveal distinct mutational signatures associated with inflammatory microenvironme...

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Autores principales: Cheng Wang, Rong Yin, Juncheng Dai, Yayun Gu, Shaohua Cui, Hongxia Ma, Zhihong Zhang, Jiaqi Huang, Na Qin, Tao Jiang, Liguo Geng, Meng Zhu, Zhening Pu, Fangzhi Du, Yuzhuo Wang, Jianshui Yang, Liang Chen, Qianghu Wang, Yue Jiang, Lili Dong, Yihong Yao, Guangfu Jin, Zhibin Hu, Liyan Jiang, Lin Xu, Hongbing Shen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d24193983030499296dff8151ced04f2
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spelling oai:doaj.org-article:d24193983030499296dff8151ced04f22021-12-02T17:32:45ZWhole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients10.1038/s41467-018-04492-22041-1723https://doaj.org/article/d24193983030499296dff8151ced04f22018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04492-2https://doaj.org/toc/2041-1723The distinct genomic and epidemiological features of Chinese lung cancer patients suggest the presence of alternative causal mechanisms. Here, the authors present the genomic landscape of 149 Chinese NSCLC patients and reveal distinct mutational signatures associated with inflammatory microenvironments.Cheng WangRong YinJuncheng DaiYayun GuShaohua CuiHongxia MaZhihong ZhangJiaqi HuangNa QinTao JiangLiguo GengMeng ZhuZhening PuFangzhi DuYuzhuo WangJianshui YangLiang ChenQianghu WangYue JiangLili DongYihong YaoGuangfu JinZhibin HuLiyan JiangLin XuHongbing ShenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Cheng Wang
Rong Yin
Juncheng Dai
Yayun Gu
Shaohua Cui
Hongxia Ma
Zhihong Zhang
Jiaqi Huang
Na Qin
Tao Jiang
Liguo Geng
Meng Zhu
Zhening Pu
Fangzhi Du
Yuzhuo Wang
Jianshui Yang
Liang Chen
Qianghu Wang
Yue Jiang
Lili Dong
Yihong Yao
Guangfu Jin
Zhibin Hu
Liyan Jiang
Lin Xu
Hongbing Shen
Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
description The distinct genomic and epidemiological features of Chinese lung cancer patients suggest the presence of alternative causal mechanisms. Here, the authors present the genomic landscape of 149 Chinese NSCLC patients and reveal distinct mutational signatures associated with inflammatory microenvironments.
format article
author Cheng Wang
Rong Yin
Juncheng Dai
Yayun Gu
Shaohua Cui
Hongxia Ma
Zhihong Zhang
Jiaqi Huang
Na Qin
Tao Jiang
Liguo Geng
Meng Zhu
Zhening Pu
Fangzhi Du
Yuzhuo Wang
Jianshui Yang
Liang Chen
Qianghu Wang
Yue Jiang
Lili Dong
Yihong Yao
Guangfu Jin
Zhibin Hu
Liyan Jiang
Lin Xu
Hongbing Shen
author_facet Cheng Wang
Rong Yin
Juncheng Dai
Yayun Gu
Shaohua Cui
Hongxia Ma
Zhihong Zhang
Jiaqi Huang
Na Qin
Tao Jiang
Liguo Geng
Meng Zhu
Zhening Pu
Fangzhi Du
Yuzhuo Wang
Jianshui Yang
Liang Chen
Qianghu Wang
Yue Jiang
Lili Dong
Yihong Yao
Guangfu Jin
Zhibin Hu
Liyan Jiang
Lin Xu
Hongbing Shen
author_sort Cheng Wang
title Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
title_short Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
title_full Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
title_fullStr Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
title_full_unstemmed Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients
title_sort whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in chinese nsclc patients
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/d24193983030499296dff8151ced04f2
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