Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo

Abstract In a secondary dengue virus (DENV) infection, the presence of non-neutralizing antibodies (Abs), developed during a previous infection with a different DENV serotype, is thought to worsen clinical outcomes by enhancing viral production. This phenomenon is called antibody-dependent enhanceme...

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Autores principales: Takeshi Kurosu, Keiko Hanabara, Azusa Asai, Sabar Pambudi, Supranee Phanthanawiboon, Magot Diata Omokoko, Ken-ichiro Ono, Masayuki Saijo, Pongrama Ramasoota, Kazuyoshi Ikuta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d24c59de6d7345e49015206dc1b7a441
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