Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo

Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo

Abstract In a secondary dengue virus (DENV) infection, the presence of non-neutralizing antibodies (Abs), developed during a previous infection with a different DENV serotype, is thought to worsen clinical outcomes by enhancing viral production. This phenomenon is called antibody-dependent enhanceme...

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Autores principales: Takeshi Kurosu, Keiko Hanabara, Azusa Asai, Sabar Pambudi, Supranee Phanthanawiboon, Magot Diata Omokoko, Ken-ichiro Ono, Masayuki Saijo, Pongrama Ramasoota, Kazuyoshi Ikuta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/d24c59de6d7345e49015206dc1b7a441
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