Dynamic and static overloading induce early degenerative processes in caprine lumbar intervertebral discs.

Mechanical overloading of the spine is associated with low back pain and intervertebral disc (IVD) degeneration. How excessive loading elicits degenerative changes in the IVD is poorly understood. Comprehensive knowledge of the interaction between mechanical loading, cell responses and changes in th...

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Bibliographic Details
Main Authors: Cornelis P L Paul, Tom Schoorl, Hendrik A Zuiderbaan, Behrouz Zandieh Doulabi, Albert J van der Veen, Peter M van de Ven, Theo H Smit, Barend J van Royen, Marco N Helder, Margriet G Mullender
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/d259347c37d04b19aeae82cea76c96e4
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