Identity-by-descent mapping to detect rare variants conferring susceptibility to multiple sclerosis.

Identity-by-descent mapping to detect rare variants conferring susceptibility to multiple sclerosis.

Genome-wide association studies (GWAS) have identified around 60 common variants associated with multiple sclerosis (MS), but these loci only explain a fraction of the heritability of MS. Some missing heritability may be caused by rare variants that have been suggested to play an important role in t...

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Autores principales: Rui Lin, Jac Charlesworth, Jim Stankovich, Victoria M Perreau, Matthew A Brown, ANZgene Consortium, Bruce V Taylor
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d25e2232bc334290992608243f48933a
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