Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection

The new coronavirus SARS-CoV-2 was identified to be responsible for the COVID-19 pandemic. There are striking differences in the response to infection, some people develop no or mild symptoms, while other outcomes are severe of even fatal. For those COVID-19 patients who require hospitalization, pro...

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Autores principales:	Fuchs Dietmar, Gisslen Magnus
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	covid-19 neopterin laboratory diagnostic Crystallography QD901-999
Acceso en línea:	https://doaj.org/article/d25e83eb157a4f23b6dec54a3649c65b
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spelling	oai:doaj.org-article:d25e83eb157a4f23b6dec54a3649c65b2021-12-05T14:11:02ZLaboratory diagnostic value of neopterin measurements in patients with COVID-19 infection0933-48072195-472010.1515/pteridines-2021-0001https://doaj.org/article/d25e83eb157a4f23b6dec54a3649c65b2021-01-01T00:00:00Zhttps://doi.org/10.1515/pteridines-2021-0001https://doaj.org/toc/0933-4807https://doaj.org/toc/2195-4720The new coronavirus SARS-CoV-2 was identified to be responsible for the COVID-19 pandemic. There are striking differences in the response to infection, some people develop no or mild symptoms, while other outcomes are severe of even fatal. For those COVID-19 patients who require hospitalization, prognostic markers could help clinicians to identify patients with a poor outcome early. The serum levels of the immune activation marker neopterin have already been shown to be of prognostic value in patients with SARS-CoV-1 and a similar pattern can be observed for SARS-CoV-2. This comment discusses the biochemical circuits that support the clinical value of neopterin measurements in COVID-19 patients.Fuchs DietmarGisslen MagnusDe Gruyterarticlecovid-19neopterinlaboratory diagnosticCrystallographyQD901-999ENPteridines, Vol 32, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 neopterin laboratory diagnostic Crystallography QD901-999
spellingShingle	covid-19 neopterin laboratory diagnostic Crystallography QD901-999 Fuchs Dietmar Gisslen Magnus Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection
description	The new coronavirus SARS-CoV-2 was identified to be responsible for the COVID-19 pandemic. There are striking differences in the response to infection, some people develop no or mild symptoms, while other outcomes are severe of even fatal. For those COVID-19 patients who require hospitalization, prognostic markers could help clinicians to identify patients with a poor outcome early. The serum levels of the immune activation marker neopterin have already been shown to be of prognostic value in patients with SARS-CoV-1 and a similar pattern can be observed for SARS-CoV-2. This comment discusses the biochemical circuits that support the clinical value of neopterin measurements in COVID-19 patients.
format	article
author	Fuchs Dietmar Gisslen Magnus
author_facet	Fuchs Dietmar Gisslen Magnus
author_sort	Fuchs Dietmar
title	Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection
title_short	Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection
title_full	Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection
title_fullStr	Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection
title_full_unstemmed	Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection
title_sort	laboratory diagnostic value of neopterin measurements in patients with covid-19 infection
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/d25e83eb157a4f23b6dec54a3649c65b
work_keys_str_mv	AT fuchsdietmar laboratorydiagnosticvalueofneopterinmeasurementsinpatientswithcovid19infection AT gisslenmagnus laboratorydiagnosticvalueofneopterinmeasurementsinpatientswithcovid19infection
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Laboratory diagnostic value of neopterin measurements in patients with COVID-19 infection

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