The G protein coupled receptor CXCR4 designed by the QTY code becomes more hydrophilic and retains cell signaling activity

Abstract G protein-coupled receptors (GPCRs) are vital for diverse biological functions, including vision, smell, and aging. They are involved in a wide range of diseases, and are among the most important targets of medicinal drugs. Tools that facilitate GPCR studies or GPCR-based technologies or th...

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Autores principales: Lotta Tegler, Karolina Corin, Horst Pick, Jennifer Brookes, Michael Skuhersky, Horst Vogel, Shuguang Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d25ff2f655d440be8967bb59115106d6
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