Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus

Aim. To analyse frequency distribution of alleles and genotypes of -23 HphI, a polymorphic marker of the INS gene, for evaluation of its associationwith DM1. Materials and methods. The study included two group of subjects: healthy ones and DM1 patients. Genotyping was performed by real time amplif...

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Autores principales:	Aleksey Georgievich Nikitin, Elena Yur'evna Lavrikova, Yury Alexandrovich Seregin, Lyubov' Iosifovna Zil'berman, Nana Mikhailovna Tsitlidze, Tamara Leonidovna Kuraeva, Valentina Alexandrovna Peterkova, Ivan Ivanovich Dedov, Valery Vyacheslavovich Nosikov
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2010
Materias:	23hphi ins type 1 diabetes mellitus polymorphic marker -23 hphi association Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/d261d91c28094ccfb39f90ad1d8ad3d2
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spelling	oai:doaj.org-article:d261d91c28094ccfb39f90ad1d8ad3d22021-11-14T09:00:14ZAssociation of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus2072-03512072-037810.14341/2072-0351-5668https://doaj.org/article/d261d91c28094ccfb39f90ad1d8ad3d22010-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5668https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To analyse frequency distribution of alleles and genotypes of -23 HphI, a polymorphic marker of the INS gene, for evaluation of its associationwith DM1. Materials and methods. The study included two group of subjects: healthy ones and DM1 patients. Genotyping was performed by real time amplification. Results. Comparative analysis demonstrated association between -23 HphI polymorphic marker of INS gene, and type 1 diabetes mellitus. Conclusion. The use of the case-control method revealed association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus.Aleksey Georgievich NikitinElena Yur'evna LavrikovaYury Alexandrovich SereginLyubov' Iosifovna Zil'bermanNana Mikhailovna TsitlidzeTamara Leonidovna KuraevaValentina Alexandrovna PeterkovaIvan Ivanovich DedovValery Vyacheslavovich NosikovEndocrinology Research Centrearticle23hphiinstype 1 diabetes mellituspolymorphic marker-23 hphiinsassociationNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 2, Pp 17-20 (2010)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	23hphi ins type 1 diabetes mellitus polymorphic marker -23 hphi ins association Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	23hphi ins type 1 diabetes mellitus polymorphic marker -23 hphi ins association Nutritional diseases. Deficiency diseases RC620-627 Aleksey Georgievich Nikitin Elena Yur'evna Lavrikova Yury Alexandrovich Seregin Lyubov' Iosifovna Zil'berman Nana Mikhailovna Tsitlidze Tamara Leonidovna Kuraeva Valentina Alexandrovna Peterkova Ivan Ivanovich Dedov Valery Vyacheslavovich Nosikov Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus
description	Aim. To analyse frequency distribution of alleles and genotypes of -23 HphI, a polymorphic marker of the INS gene, for evaluation of its associationwith DM1. Materials and methods. The study included two group of subjects: healthy ones and DM1 patients. Genotyping was performed by real time amplification. Results. Comparative analysis demonstrated association between -23 HphI polymorphic marker of INS gene, and type 1 diabetes mellitus. Conclusion. The use of the case-control method revealed association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus.
format	article
author	Aleksey Georgievich Nikitin Elena Yur'evna Lavrikova Yury Alexandrovich Seregin Lyubov' Iosifovna Zil'berman Nana Mikhailovna Tsitlidze Tamara Leonidovna Kuraeva Valentina Alexandrovna Peterkova Ivan Ivanovich Dedov Valery Vyacheslavovich Nosikov
author_facet	Aleksey Georgievich Nikitin Elena Yur'evna Lavrikova Yury Alexandrovich Seregin Lyubov' Iosifovna Zil'berman Nana Mikhailovna Tsitlidze Tamara Leonidovna Kuraeva Valentina Alexandrovna Peterkova Ivan Ivanovich Dedov Valery Vyacheslavovich Nosikov
author_sort	Aleksey Georgievich Nikitin
title	Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus
title_short	Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus
title_full	Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus
title_fullStr	Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus
title_full_unstemmed	Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus
title_sort	association of -23 hphi, a polymorphic marker of the ins gene, with type 1 diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2010
url	https://doaj.org/article/d261d91c28094ccfb39f90ad1d8ad3d2
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Association of -23 HphI, a polymorphic marker of the INS gene, with type 1 diabetes mellitus

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