Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver
Abstract Recent studies demonstrated reduced blood lysosomal acid lipase (LAL) activity in patients with nonalcoholic fatty liver disease (NAFLD). We aimed to verify hepatic LAL protein content and activity in in vitro and in vivo models of fat overload and in NAFLD patients. LAL protein content and...
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Autores principales: | Simone Carotti, Daniele Lettieri-Barbato, Fiorella Piemonte, Sergio Ruggiero, Marco Rosina, Francesca Zalfa, Maria Zingariello, Francesca Arciprete, Francesco Valentini, Maria Francesconi, Jessica D’Amico, Antonio De Vincentis, Andrea Baiocchini, Giuseppe Perrone, Raffaele Antonelli-Incalzi, Sergio Morini, Antonio Picardi, Katia Aquilano, Umberto Vespasiani-Gentilucci |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d2687a261333480896347537214e9a61 |
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