Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.

<h4>Objective</h4>To determine risk factors of superimposed preeclampsia in women with essential chronic hypertension receiving antihypertensive therapy prior to conception.<h4>Methods</h4>A retrospective study of 211 patients that analyzed risk factors of superimposed preecl...

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Auteurs principaux:	Edouard Lecarpentier, Vassilis Tsatsaris, François Goffinet, Dominique Cabrol, Baha Sibai, Bassam Haddad
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2013
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/d26a2aebb4ac4d0a9401129c6767fd49
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spelling	oai:doaj.org-article:d26a2aebb4ac4d0a9401129c6767fd492021-11-18T07:46:50ZRisk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.1932-620310.1371/journal.pone.0062140https://doaj.org/article/d26a2aebb4ac4d0a9401129c6767fd492013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23671584/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>To determine risk factors of superimposed preeclampsia in women with essential chronic hypertension receiving antihypertensive therapy prior to conception.<h4>Methods</h4>A retrospective study of 211 patients that analyzed risk factors of superimposed preeclampsia at first prenatal visit. Variables with a p<.1 at univariate analysis were included in a logistic regression analysis. P<.05 was considered as significant.<h4>Results</h4>Superimposed preeclampsia occurred in 49 (23.2%) women. In logistic regression analysis, previous preeclampsia [OR: 4.05 (1.61-10.16)], and mean arterial blood pressure of 95 mmHg or higher [OR: 4.60 (1.94-10.93)] were associated with increased risk of superimposed preeclampsia. When both variables were present, sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratio for superimposed preeclampsia were 43%, 94%, 70%, 85%, and 7.71 (95% CI: 3.20-18.57), respectively.<h4>Conclusion</h4>In essential chronic hypertensive women, previous preeclampsia and mean arterial blood pressure of 95 mmHg or higher are associated with increased risks of superimposed preeclampsia.Edouard LecarpentierVassilis TsatsarisFrançois GoffinetDominique CabrolBaha SibaiBassam HaddadPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 5, p e62140 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Edouard Lecarpentier Vassilis Tsatsaris François Goffinet Dominique Cabrol Baha Sibai Bassam Haddad Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
description	<h4>Objective</h4>To determine risk factors of superimposed preeclampsia in women with essential chronic hypertension receiving antihypertensive therapy prior to conception.<h4>Methods</h4>A retrospective study of 211 patients that analyzed risk factors of superimposed preeclampsia at first prenatal visit. Variables with a p<.1 at univariate analysis were included in a logistic regression analysis. P<.05 was considered as significant.<h4>Results</h4>Superimposed preeclampsia occurred in 49 (23.2%) women. In logistic regression analysis, previous preeclampsia [OR: 4.05 (1.61-10.16)], and mean arterial blood pressure of 95 mmHg or higher [OR: 4.60 (1.94-10.93)] were associated with increased risk of superimposed preeclampsia. When both variables were present, sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratio for superimposed preeclampsia were 43%, 94%, 70%, 85%, and 7.71 (95% CI: 3.20-18.57), respectively.<h4>Conclusion</h4>In essential chronic hypertensive women, previous preeclampsia and mean arterial blood pressure of 95 mmHg or higher are associated with increased risks of superimposed preeclampsia.
format	article
author	Edouard Lecarpentier Vassilis Tsatsaris François Goffinet Dominique Cabrol Baha Sibai Bassam Haddad
author_facet	Edouard Lecarpentier Vassilis Tsatsaris François Goffinet Dominique Cabrol Baha Sibai Bassam Haddad
author_sort	Edouard Lecarpentier
title	Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
title_short	Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
title_full	Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
title_fullStr	Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
title_full_unstemmed	Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
title_sort	risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/d26a2aebb4ac4d0a9401129c6767fd49
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Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.

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