L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast

The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events.

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Autores principales: Lena Hochrein, Leslie A. Mitchell, Karina Schulz, Katrin Messerschmidt, Bernd Mueller-Roeber
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d26c1b18aa1343b1b6443c240f39a31a
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spelling oai:doaj.org-article:d26c1b18aa1343b1b6443c240f39a31a2021-12-02T16:50:11ZL-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast10.1038/s41467-017-02208-62041-1723https://doaj.org/article/d26c1b18aa1343b1b6443c240f39a31a2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02208-6https://doaj.org/toc/2041-1723The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events.Lena HochreinLeslie A. MitchellKarina SchulzKatrin MesserschmidtBernd Mueller-RoeberNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lena Hochrein
Leslie A. Mitchell
Karina Schulz
Katrin Messerschmidt
Bernd Mueller-Roeber
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
description The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events.
format article
author Lena Hochrein
Leslie A. Mitchell
Karina Schulz
Katrin Messerschmidt
Bernd Mueller-Roeber
author_facet Lena Hochrein
Leslie A. Mitchell
Karina Schulz
Katrin Messerschmidt
Bernd Mueller-Roeber
author_sort Lena Hochrein
title L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
title_short L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
title_full L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
title_fullStr L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
title_full_unstemmed L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
title_sort l-scramble as a tool for light-controlled cre-mediated recombination in yeast
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/d26c1b18aa1343b1b6443c240f39a31a
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AT leslieamitchell lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast
AT karinaschulz lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast
AT katrinmesserschmidt lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast
AT berndmuellerroeber lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast
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