L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events.
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Nature Portfolio
2018
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oai:doaj.org-article:d26c1b18aa1343b1b6443c240f39a31a2021-12-02T16:50:11ZL-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast10.1038/s41467-017-02208-62041-1723https://doaj.org/article/d26c1b18aa1343b1b6443c240f39a31a2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02208-6https://doaj.org/toc/2041-1723The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events.Lena HochreinLeslie A. MitchellKarina SchulzKatrin MesserschmidtBernd Mueller-RoeberNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Lena Hochrein Leslie A. Mitchell Karina Schulz Katrin Messerschmidt Bernd Mueller-Roeber L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast |
description |
The International Synthetic Yeast Sc2.0 project has built Cre recombinase sites into synthetic chromosomes, enabling rapid genome evolution. Here the authors demonstrate L-SCRaMbLE, a light-controlled recombinase tool with improved control over recombination events. |
format |
article |
author |
Lena Hochrein Leslie A. Mitchell Karina Schulz Katrin Messerschmidt Bernd Mueller-Roeber |
author_facet |
Lena Hochrein Leslie A. Mitchell Karina Schulz Katrin Messerschmidt Bernd Mueller-Roeber |
author_sort |
Lena Hochrein |
title |
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast |
title_short |
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast |
title_full |
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast |
title_fullStr |
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast |
title_full_unstemmed |
L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast |
title_sort |
l-scramble as a tool for light-controlled cre-mediated recombination in yeast |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/d26c1b18aa1343b1b6443c240f39a31a |
work_keys_str_mv |
AT lenahochrein lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast AT leslieamitchell lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast AT karinaschulz lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast AT katrinmesserschmidt lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast AT berndmuellerroeber lscrambleasatoolforlightcontrolledcremediatedrecombinationinyeast |
_version_ |
1718383125882470400 |