Ambient air pollution exposure and thyroid cancer incidence in Iran

Introduction: Thyroid cancer is the most common endocrine malignant that is three times more prevalent in women than men. Fine particulate matter (PM2.5( has been indicated to affect Thyroid Hormone (TH) homeostasis. We sought to estimate the association between long-term exposure to ambient air po...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Samaneh Dehghani, Mohebat Vali, Arefe Abedinzade
Formato:	article
Lenguaje:	EN
Publicado:	Tehran University of Medical Sciences 2021
Materias:	Particulate matter 2.5 (PM2.5); Thyroid cancer; Air pollution; Cancer Environmental technology. Sanitary engineering TD1-1066
Acceso en línea:	https://doaj.org/article/d26fdc171f4146e1bf9bf26728081e76
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d26fdc171f4146e1bf9bf26728081e76
record_format	dspace
spelling	oai:doaj.org-article:d26fdc171f4146e1bf9bf26728081e762021-11-20T05:13:26ZAmbient air pollution exposure and thyroid cancer incidence in Iran10.18502/japh.v6i1.76032476-3071https://doaj.org/article/d26fdc171f4146e1bf9bf26728081e762021-10-01T00:00:00Zhttps://japh.tums.ac.ir/index.php/japh/article/view/288https://doaj.org/toc/2476-3071 Introduction: Thyroid cancer is the most common endocrine malignant that is three times more prevalent in women than men. Fine particulate matter (PM2.5( has been indicated to affect Thyroid Hormone (TH) homeostasis. We sought to estimate the association between long-term exposure to ambient air pollution and the incidence of thyroid cancer in the Iranian female population. Materials and methods: We extracted thyroid cancer incidence and ambient air pollution data from Iran from 2000 to 2019 for males and females for all age groups from the Global Burden of Disease (GBD) dataset. We entered the data into Joinpoint to present Annual Percent Change (APC) and Average Annual Percent Change (AAPC) and its confidence intervals. We entered the information into R3.5.0. Results: Thyroid cancer in females had an upward trend [AAPC=4.9% (4.2-5.6)]. There was a correlation between ambient PM pollution (p≤0.001, r=0.84) and ambient ozone pollution (p≤0.001, r=0.94), and the incidence of thyroid cancer in females. The results of the analysis also showed a significant relationship between thyroid cancer incidence in females and secondhand smoke (p≤0.001, r=0.74). Conclusion: This study indicated increasing trends in thyroid cancer incidence with exposure to ambient air pollution. Our novel findings provide additional insight into the potential associations between risk factors and thyroid cancer and warrant further investigation, specifically in areas with high levels of air pollution both nationally and internationally. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on Iran. Samaneh DehghaniMohebat ValiArefe AbedinzadeTehran University of Medical SciencesarticleParticulate matter 2.5 (PM2.5); Thyroid cancer; Air pollution; CancerEnvironmental technology. Sanitary engineeringTD1-1066ENJournal of Air Pollution and Health, Vol 6, Iss 1 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Particulate matter 2.5 (PM2.5); Thyroid cancer; Air pollution; Cancer Environmental technology. Sanitary engineering TD1-1066
spellingShingle	Particulate matter 2.5 (PM2.5); Thyroid cancer; Air pollution; Cancer Environmental technology. Sanitary engineering TD1-1066 Samaneh Dehghani Mohebat Vali Arefe Abedinzade Ambient air pollution exposure and thyroid cancer incidence in Iran
description	Introduction: Thyroid cancer is the most common endocrine malignant that is three times more prevalent in women than men. Fine particulate matter (PM2.5( has been indicated to affect Thyroid Hormone (TH) homeostasis. We sought to estimate the association between long-term exposure to ambient air pollution and the incidence of thyroid cancer in the Iranian female population. Materials and methods: We extracted thyroid cancer incidence and ambient air pollution data from Iran from 2000 to 2019 for males and females for all age groups from the Global Burden of Disease (GBD) dataset. We entered the data into Joinpoint to present Annual Percent Change (APC) and Average Annual Percent Change (AAPC) and its confidence intervals. We entered the information into R3.5.0. Results: Thyroid cancer in females had an upward trend [AAPC=4.9% (4.2-5.6)]. There was a correlation between ambient PM pollution (p≤0.001, r=0.84) and ambient ozone pollution (p≤0.001, r=0.94), and the incidence of thyroid cancer in females. The results of the analysis also showed a significant relationship between thyroid cancer incidence in females and secondhand smoke (p≤0.001, r=0.74). Conclusion: This study indicated increasing trends in thyroid cancer incidence with exposure to ambient air pollution. Our novel findings provide additional insight into the potential associations between risk factors and thyroid cancer and warrant further investigation, specifically in areas with high levels of air pollution both nationally and internationally. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on Iran.
format	article
author	Samaneh Dehghani Mohebat Vali Arefe Abedinzade
author_facet	Samaneh Dehghani Mohebat Vali Arefe Abedinzade
author_sort	Samaneh Dehghani
title	Ambient air pollution exposure and thyroid cancer incidence in Iran
title_short	Ambient air pollution exposure and thyroid cancer incidence in Iran
title_full	Ambient air pollution exposure and thyroid cancer incidence in Iran
title_fullStr	Ambient air pollution exposure and thyroid cancer incidence in Iran
title_full_unstemmed	Ambient air pollution exposure and thyroid cancer incidence in Iran
title_sort	ambient air pollution exposure and thyroid cancer incidence in iran
publisher	Tehran University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/d26fdc171f4146e1bf9bf26728081e76
work_keys_str_mv	AT samanehdehghani ambientairpollutionexposureandthyroidcancerincidenceiniran AT mohebatvali ambientairpollutionexposureandthyroidcancerincidenceiniran AT arefeabedinzade ambientairpollutionexposureandthyroidcancerincidenceiniran
_version_	1718419570290589696

Ambient air pollution exposure and thyroid cancer incidence in Iran

Ejemplares similares