How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence

The “no dose is safe” linear no-threshold (LNT) model forms the basis for radiation safety in radiology practice. This model has its origins in observations of germline mutations in fruit flies exposed to X-rays. After World War II, quantitative risk estimates of radiation injury are primarily deriv...

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Autor principal:	Srikanth Moorthy
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Materias:	radiation dose radiology safety history Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/d275383266b248d38cbdea0bd1388902
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spelling	oai:doaj.org-article:d275383266b248d38cbdea0bd13889022021-11-13T23:32:30ZHow Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence0971-30261998-380810.1055/s-0041-1735927https://doaj.org/article/d275383266b248d38cbdea0bd13889022021-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1735927https://doaj.org/toc/0971-3026https://doaj.org/toc/1998-3808The “no dose is safe” linear no-threshold (LNT) model forms the basis for radiation safety in radiology practice. This model has its origins in observations of germline mutations in fruit flies exposed to X-rays. After World War II, quantitative risk estimates of radiation injury are primarily derived from the atomic bomb survivor Life Span Study. Current understanding of tissue response to radiation has raised doubts about the validity of LNT model at low doses encountered in the practice of diagnostic radiology. This article traces the evolution of basic radiation safety concepts and provides a bird's eye view of the Life Span Study and other studies which throw light on the matter. The arguments for an alternative, threshold, or even hermetic models of dose response are examined. The relevance of these developments to the nuclear power industry is also outlined.Srikanth MoorthyThieme Medical and Scientific Publishers Pvt. Ltd.articleradiationdoseradiologysafetyhistoryMedical physics. Medical radiology. Nuclear medicineR895-920ENIndian Journal of Radiology and Imaging, Vol 31, Iss 03, Pp 653-660 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	radiation dose radiology safety history Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	radiation dose radiology safety history Medical physics. Medical radiology. Nuclear medicine R895-920 Srikanth Moorthy How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
description	The “no dose is safe” linear no-threshold (LNT) model forms the basis for radiation safety in radiology practice. This model has its origins in observations of germline mutations in fruit flies exposed to X-rays. After World War II, quantitative risk estimates of radiation injury are primarily derived from the atomic bomb survivor Life Span Study. Current understanding of tissue response to radiation has raised doubts about the validity of LNT model at low doses encountered in the practice of diagnostic radiology. This article traces the evolution of basic radiation safety concepts and provides a bird's eye view of the Life Span Study and other studies which throw light on the matter. The arguments for an alternative, threshold, or even hermetic models of dose response are examined. The relevance of these developments to the nuclear power industry is also outlined.
format	article
author	Srikanth Moorthy
author_facet	Srikanth Moorthy
author_sort	Srikanth Moorthy
title	How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
title_short	How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
title_full	How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
title_fullStr	How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
title_full_unstemmed	How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
title_sort	how safe are radiation doses in diagnostic radiology? a historical perspective and review of current evidence
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2021
url	https://doaj.org/article/d275383266b248d38cbdea0bd1388902
work_keys_str_mv	AT srikanthmoorthy howsafeareradiationdosesindiagnosticradiologyahistoricalperspectiveandreviewofcurrentevidence
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How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence

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