A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.

Serratia plymuthica strain RVH1, initially isolated from an industrial food processing environment, displays potent antimicrobial activity towards a broad spectrum of Gram-positive and Gram-negative bacterial pathogens. Isolation and subsequent structure determination of bioactive molecules led to t...

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Autores principales: Joleen Masschelein, Wesley Mattheus, Ling-Jie Gao, Pieter Moons, Rob Van Houdt, Birgit Uytterhoeven, Chris Lamberigts, Eveline Lescrinier, Jef Rozenski, Piet Herdewijn, Abram Aertsen, Chris Michiels, Rob Lavigne
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d276ab8c844a4082a283dce5fd4294b9
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