Integrated genomic analyses of de novo pathways underlying atypical meningiomas
Meningiomas are mostly benign brain tumours with the potential for becoming atypical or malignant. Here, the authors show that primary atypical meningiomas are epigenetically and genetically distinct from benign and progressed tumours, highlighting possible therapeutic targets such as PRC2.
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Nature Portfolio
2017
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oai:doaj.org-article:d27c23c5f6b847e4a5ce5684ebe1b3562021-12-02T14:41:11ZIntegrated genomic analyses of de novo pathways underlying atypical meningiomas10.1038/ncomms144332041-1723https://doaj.org/article/d27c23c5f6b847e4a5ce5684ebe1b3562017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14433https://doaj.org/toc/2041-1723Meningiomas are mostly benign brain tumours with the potential for becoming atypical or malignant. Here, the authors show that primary atypical meningiomas are epigenetically and genetically distinct from benign and progressed tumours, highlighting possible therapeutic targets such as PRC2.Akdes Serin HarmancıMark W. YoungbloodVictoria E. ClarkSüleyman CoşkunOctavian HenegariuDaniel DuranE. Zeynep Erson-OmayLeon D. KaulenTong Ihn LeeBrian J. AbrahamMatthias SimonBoris KrischekMarco TimmerRoland GoldbrunnerS. Bülent OmayJacob BaranoskiBurçin BaranGeneive Carrión-GrantHanwen BaiKetu Mishra-GorurJohannes SchrammJennifer MoliternoAlexander O. VortmeyerKaya BilgüvarKatsuhito YasunoRichard A. YoungMurat GünelNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q |
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Science Q Akdes Serin Harmancı Mark W. Youngblood Victoria E. Clark Süleyman Coşkun Octavian Henegariu Daniel Duran E. Zeynep Erson-Omay Leon D. Kaulen Tong Ihn Lee Brian J. Abraham Matthias Simon Boris Krischek Marco Timmer Roland Goldbrunner S. Bülent Omay Jacob Baranoski Burçin Baran Geneive Carrión-Grant Hanwen Bai Ketu Mishra-Gorur Johannes Schramm Jennifer Moliterno Alexander O. Vortmeyer Kaya Bilgüvar Katsuhito Yasuno Richard A. Young Murat Günel Integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| description |
Meningiomas are mostly benign brain tumours with the potential for becoming atypical or malignant. Here, the authors show that primary atypical meningiomas are epigenetically and genetically distinct from benign and progressed tumours, highlighting possible therapeutic targets such as PRC2. |
| format |
article |
| author |
Akdes Serin Harmancı Mark W. Youngblood Victoria E. Clark Süleyman Coşkun Octavian Henegariu Daniel Duran E. Zeynep Erson-Omay Leon D. Kaulen Tong Ihn Lee Brian J. Abraham Matthias Simon Boris Krischek Marco Timmer Roland Goldbrunner S. Bülent Omay Jacob Baranoski Burçin Baran Geneive Carrión-Grant Hanwen Bai Ketu Mishra-Gorur Johannes Schramm Jennifer Moliterno Alexander O. Vortmeyer Kaya Bilgüvar Katsuhito Yasuno Richard A. Young Murat Günel |
| author_facet |
Akdes Serin Harmancı Mark W. Youngblood Victoria E. Clark Süleyman Coşkun Octavian Henegariu Daniel Duran E. Zeynep Erson-Omay Leon D. Kaulen Tong Ihn Lee Brian J. Abraham Matthias Simon Boris Krischek Marco Timmer Roland Goldbrunner S. Bülent Omay Jacob Baranoski Burçin Baran Geneive Carrión-Grant Hanwen Bai Ketu Mishra-Gorur Johannes Schramm Jennifer Moliterno Alexander O. Vortmeyer Kaya Bilgüvar Katsuhito Yasuno Richard A. Young Murat Günel |
| author_sort |
Akdes Serin Harmancı |
| title |
Integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| title_short |
Integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| title_full |
Integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| title_fullStr |
Integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| title_full_unstemmed |
Integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| title_sort |
integrated genomic analyses of de novo pathways underlying atypical meningiomas |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/d27c23c5f6b847e4a5ce5684ebe1b356 |
| work_keys_str_mv |
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| _version_ |
1718390022813515776 |