Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing

Abstract The paper examines the development and testing of an electro-pneumatic device for wound healing therapy after surgery in the neck area. The device generates air pressure values in a miniaturized cuff using electronic circuitry to drive an electro-valve and air compressor. The device works i...

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Autores principales:	J. Foltyn, A. Proto, D. Oczka, R. Halfar, T. Klinkovsky, L. Skoloudik, M. Cerny, V. Chrobok, A. Ryska, V. Radochova, M. Litschmannova, M. Penhaker, J. Mejzlik
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d284465f256748638ab9514bd02d29b4
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spelling	oai:doaj.org-article:d284465f256748638ab9514bd02d29b42021-12-02T15:09:55ZEvaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing10.1038/s41598-019-46397-02045-2322https://doaj.org/article/d284465f256748638ab9514bd02d29b42019-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-46397-0https://doaj.org/toc/2045-2322Abstract The paper examines the development and testing of an electro-pneumatic device for wound healing therapy after surgery in the neck area. The device generates air pressure values in a miniaturized cuff using electronic circuitry to drive an electro-valve and air compressor. The device works in two distinct modes: continuous pressure mode and pulsating pressure mode. The pressure value setting can vary from 3 to 11 mmHg, and the pulsating pressure mode’s operating frequency range is approximately 0.1 to 0.3 Hz. Laboratory measurements were conducted to evaluate the device’s correct functioning in both continuous and pulsating pressure modes. A four-day prospective study with animals (n = 10) was also conducted to evaluate neck wound healing therapy using the electro-pneumatic device. Out of the twelve histological parameters analysed to reveal the differences between the experimental and control wounds, only one demonstrated a significant difference. Out of the ten animals treated with the device, three showed a significant difference in terms of benefit after therapy. We can therefore conclude that the device potentially improves the wound healing process in the neck area if the pre-set air pressure value does not exceed 8 mmHg.J. FoltynA. ProtoD. OczkaR. HalfarT. KlinkovskyL. SkoloudikM. CernyV. ChrobokA. RyskaV. RadochovaM. LitschmannovaM. PenhakerJ. MejzlikNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q J. Foltyn A. Proto D. Oczka R. Halfar T. Klinkovsky L. Skoloudik M. Cerny V. Chrobok A. Ryska V. Radochova M. Litschmannova M. Penhaker J. Mejzlik Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing
description	Abstract The paper examines the development and testing of an electro-pneumatic device for wound healing therapy after surgery in the neck area. The device generates air pressure values in a miniaturized cuff using electronic circuitry to drive an electro-valve and air compressor. The device works in two distinct modes: continuous pressure mode and pulsating pressure mode. The pressure value setting can vary from 3 to 11 mmHg, and the pulsating pressure mode’s operating frequency range is approximately 0.1 to 0.3 Hz. Laboratory measurements were conducted to evaluate the device’s correct functioning in both continuous and pulsating pressure modes. A four-day prospective study with animals (n = 10) was also conducted to evaluate neck wound healing therapy using the electro-pneumatic device. Out of the twelve histological parameters analysed to reveal the differences between the experimental and control wounds, only one demonstrated a significant difference. Out of the ten animals treated with the device, three showed a significant difference in terms of benefit after therapy. We can therefore conclude that the device potentially improves the wound healing process in the neck area if the pre-set air pressure value does not exceed 8 mmHg.
format	article
author	J. Foltyn A. Proto D. Oczka R. Halfar T. Klinkovsky L. Skoloudik M. Cerny V. Chrobok A. Ryska V. Radochova M. Litschmannova M. Penhaker J. Mejzlik
author_facet	J. Foltyn A. Proto D. Oczka R. Halfar T. Klinkovsky L. Skoloudik M. Cerny V. Chrobok A. Ryska V. Radochova M. Litschmannova M. Penhaker J. Mejzlik
author_sort	J. Foltyn
title	Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing
title_short	Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing
title_full	Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing
title_fullStr	Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing
title_full_unstemmed	Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing
title_sort	evaluation of an electro-pneumatic device for artificial capillary pulse generation used in a prospective study in animals for surgical neck wound healing
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d284465f256748638ab9514bd02d29b4
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Evaluation of an Electro-Pneumatic Device for Artificial Capillary Pulse Generation used in a Prospective Study in Animals for Surgical Neck Wound Healing

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