The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Thomas Fouqueau, Fabian Blombach, Ross Hartman, Alan C. M. Cheung, Mark J. Young, Finn Werner
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/d2871d4f0e1c478a872b40aa7ab0b36d
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:d2871d4f0e1c478a872b40aa7ab0b36d
record_format	dspace
spelling	oai:doaj.org-article:d2871d4f0e1c478a872b40aa7ab0b36d2021-12-02T14:42:04ZThe transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor10.1038/s41467-017-02081-32041-1723https://doaj.org/article/d2871d4f0e1c478a872b40aa7ab0b36d2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02081-3https://doaj.org/toc/2041-1723Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense.Thomas FouqueauFabian BlombachRoss HartmanAlan C. M. CheungMark J. YoungFinn WernerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas Fouqueau Fabian Blombach Ross Hartman Alan C. M. Cheung Mark J. Young Finn Werner The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
description	Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense.
format	article
author	Thomas Fouqueau Fabian Blombach Ross Hartman Alan C. M. Cheung Mark J. Young Finn Werner
author_facet	Thomas Fouqueau Fabian Blombach Ross Hartman Alan C. M. Cheung Mark J. Young Finn Werner
author_sort	Thomas Fouqueau
title	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_short	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_full	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_fullStr	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_full_unstemmed	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_sort	transcript cleavage factor paralogue tfs4 is a potent rna polymerase inhibitor
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d2871d4f0e1c478a872b40aa7ab0b36d
work_keys_str_mv	AT thomasfouqueau thetranscriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT fabianblombach thetranscriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT rosshartman thetranscriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT alancmcheung thetranscriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT markjyoung thetranscriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT finnwerner thetranscriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT thomasfouqueau transcriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT fabianblombach transcriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT rosshartman transcriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT alancmcheung transcriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT markjyoung transcriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor AT finnwerner transcriptcleavagefactorparaloguetfs4isapotentrnapolymeraseinhibitor
_version_	1718389838530478080

The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

Documents similaires