The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense...

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Main Authors:	Thomas Fouqueau, Fabian Blombach, Ross Hartman, Alan C. M. Cheung, Mark J. Young, Finn Werner
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/d2871d4f0e1c478a872b40aa7ab0b36d
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id	oai:doaj.org-article:d2871d4f0e1c478a872b40aa7ab0b36d
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spelling	oai:doaj.org-article:d2871d4f0e1c478a872b40aa7ab0b36d2021-12-02T14:42:04ZThe transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor10.1038/s41467-017-02081-32041-1723https://doaj.org/article/d2871d4f0e1c478a872b40aa7ab0b36d2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02081-3https://doaj.org/toc/2041-1723Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense.Thomas FouqueauFabian BlombachRoss HartmanAlan C. M. CheungMark J. YoungFinn WernerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas Fouqueau Fabian Blombach Ross Hartman Alan C. M. Cheung Mark J. Young Finn Werner The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
description	Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense.
format	article
author	Thomas Fouqueau Fabian Blombach Ross Hartman Alan C. M. Cheung Mark J. Young Finn Werner
author_facet	Thomas Fouqueau Fabian Blombach Ross Hartman Alan C. M. Cheung Mark J. Young Finn Werner
author_sort	Thomas Fouqueau
title	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_short	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_full	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_fullStr	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_full_unstemmed	The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
title_sort	transcript cleavage factor paralogue tfs4 is a potent rna polymerase inhibitor
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d2871d4f0e1c478a872b40aa7ab0b36d
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The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

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