Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
Single-molecule sensing is very challenging due to weak emitted signals and environmental interference. Here the authors design a method (i-SET) for single molecule sensing with core-shell upconverting nanoparticles, which relies on signal enhancement by the activator-rich probes to quantify fluorop...
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Nature Portfolio
2020
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oai:doaj.org-article:d28b5704d1be44959aa8f253bf81b4932021-12-02T18:53:15ZSingle-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy10.1038/s41467-020-18223-z2041-1723https://doaj.org/article/d28b5704d1be44959aa8f253bf81b4932020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18223-zhttps://doaj.org/toc/2041-1723Single-molecule sensing is very challenging due to weak emitted signals and environmental interference. Here the authors design a method (i-SET) for single molecule sensing with core-shell upconverting nanoparticles, which relies on signal enhancement by the activator-rich probes to quantify fluorophores attached to a single nanoparticle.Jian ZhouChangyu LiDenghao LiXiaofeng LiuZhao MuWeibo GaoJianrong QiuRenren DengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020) |
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Science Q Jian Zhou Changyu Li Denghao Li Xiaofeng Liu Zhao Mu Weibo Gao Jianrong Qiu Renren Deng Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy |
description |
Single-molecule sensing is very challenging due to weak emitted signals and environmental interference. Here the authors design a method (i-SET) for single molecule sensing with core-shell upconverting nanoparticles, which relies on signal enhancement by the activator-rich probes to quantify fluorophores attached to a single nanoparticle. |
format |
article |
author |
Jian Zhou Changyu Li Denghao Li Xiaofeng Liu Zhao Mu Weibo Gao Jianrong Qiu Renren Deng |
author_facet |
Jian Zhou Changyu Li Denghao Li Xiaofeng Liu Zhao Mu Weibo Gao Jianrong Qiu Renren Deng |
author_sort |
Jian Zhou |
title |
Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy |
title_short |
Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy |
title_full |
Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy |
title_fullStr |
Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy |
title_full_unstemmed |
Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy |
title_sort |
single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-set) spectroscopy |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/d28b5704d1be44959aa8f253bf81b493 |
work_keys_str_mv |
AT jianzhou singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT changyuli singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT denghaoli singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT xiaofengliu singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT zhaomu singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT weibogao singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT jianrongqiu singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy AT renrendeng singlemoleculephotoreactionquantitationthroughintraparticlesurfaceenergytransferisetspectroscopy |
_version_ |
1718377354036772864 |