Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy

Single-molecule sensing is very challenging due to weak emitted signals and environmental interference. Here the authors design a method (i-SET) for single molecule sensing with core-shell upconverting nanoparticles, which relies on signal enhancement by the activator-rich probes to quantify fluorop...

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Autores principales: Jian Zhou, Changyu Li, Denghao Li, Xiaofeng Liu, Zhao Mu, Weibo Gao, Jianrong Qiu, Renren Deng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d28b5704d1be44959aa8f253bf81b493
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spelling oai:doaj.org-article:d28b5704d1be44959aa8f253bf81b4932021-12-02T18:53:15ZSingle-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy10.1038/s41467-020-18223-z2041-1723https://doaj.org/article/d28b5704d1be44959aa8f253bf81b4932020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18223-zhttps://doaj.org/toc/2041-1723Single-molecule sensing is very challenging due to weak emitted signals and environmental interference. Here the authors design a method (i-SET) for single molecule sensing with core-shell upconverting nanoparticles, which relies on signal enhancement by the activator-rich probes to quantify fluorophores attached to a single nanoparticle.Jian ZhouChangyu LiDenghao LiXiaofeng LiuZhao MuWeibo GaoJianrong QiuRenren DengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jian Zhou
Changyu Li
Denghao Li
Xiaofeng Liu
Zhao Mu
Weibo Gao
Jianrong Qiu
Renren Deng
Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
description Single-molecule sensing is very challenging due to weak emitted signals and environmental interference. Here the authors design a method (i-SET) for single molecule sensing with core-shell upconverting nanoparticles, which relies on signal enhancement by the activator-rich probes to quantify fluorophores attached to a single nanoparticle.
format article
author Jian Zhou
Changyu Li
Denghao Li
Xiaofeng Liu
Zhao Mu
Weibo Gao
Jianrong Qiu
Renren Deng
author_facet Jian Zhou
Changyu Li
Denghao Li
Xiaofeng Liu
Zhao Mu
Weibo Gao
Jianrong Qiu
Renren Deng
author_sort Jian Zhou
title Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
title_short Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
title_full Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
title_fullStr Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
title_full_unstemmed Single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-SET) spectroscopy
title_sort single-molecule photoreaction quantitation through intraparticle-surface energy transfer (i-set) spectroscopy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d28b5704d1be44959aa8f253bf81b493
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