A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure
Intraocular pressure (IOP) is a major risk factor for glaucoma. Here, Choquet and co-authors perform a multi-ethnic genome-wide association study of repeat IOP measurements in 69,756 individuals and identify 40 novel loci, 36 of which show directionally consistent effects in glaucoma.
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Nature Portfolio
2017
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oai:doaj.org-article:d28f9a2d6c08476a9173b4a2e84096892021-12-02T14:40:46ZA large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure10.1038/s41467-017-01913-62041-1723https://doaj.org/article/d28f9a2d6c08476a9173b4a2e84096892017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01913-6https://doaj.org/toc/2041-1723Intraocular pressure (IOP) is a major risk factor for glaucoma. Here, Choquet and co-authors perform a multi-ethnic genome-wide association study of repeat IOP measurements in 69,756 individuals and identify 40 novel loci, 36 of which show directionally consistent effects in glaucoma.Hélène ChoquetKhanh K. ThaiJie YinThomas J. HoffmannMark N. KvaleYambazi BandaCatherine SchaeferNeil RischK. Saidas NairRonald MellesEric JorgensonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Hélène Choquet Khanh K. Thai Jie Yin Thomas J. Hoffmann Mark N. Kvale Yambazi Banda Catherine Schaefer Neil Risch K. Saidas Nair Ronald Melles Eric Jorgenson A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| description |
Intraocular pressure (IOP) is a major risk factor for glaucoma. Here, Choquet and co-authors perform a multi-ethnic genome-wide association study of repeat IOP measurements in 69,756 individuals and identify 40 novel loci, 36 of which show directionally consistent effects in glaucoma. |
| format |
article |
| author |
Hélène Choquet Khanh K. Thai Jie Yin Thomas J. Hoffmann Mark N. Kvale Yambazi Banda Catherine Schaefer Neil Risch K. Saidas Nair Ronald Melles Eric Jorgenson |
| author_facet |
Hélène Choquet Khanh K. Thai Jie Yin Thomas J. Hoffmann Mark N. Kvale Yambazi Banda Catherine Schaefer Neil Risch K. Saidas Nair Ronald Melles Eric Jorgenson |
| author_sort |
Hélène Choquet |
| title |
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| title_short |
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| title_full |
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| title_fullStr |
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| title_full_unstemmed |
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| title_sort |
large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/d28f9a2d6c08476a9173b4a2e8409689 |
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