Persistence against benzalkonium chloride promotes rapid evolution of tolerance during periodic disinfection

Phenotypically tolerant, persister bacterial subpopulations can survive transient antibiotic treatment and facilitate resistance evolution. Here, Nordholt et al. show that E. coli can display persistence against a widely used disinfectant and this is associated with alterations in the cell surface a...

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Autores principales: Niclas Nordholt, Orestis Kanaris, Selina B. I. Schmidt, Frank Schreiber
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d28feceec5e440e6a3aacfd2811aa663
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Sumario:Phenotypically tolerant, persister bacterial subpopulations can survive transient antibiotic treatment and facilitate resistance evolution. Here, Nordholt et al. show that E. coli can display persistence against a widely used disinfectant and this is associated with alterations in the cell surface and with antibiotic tolerance.